Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | K8227_RS09420 | Genome accession | NZ_CP082948 |
| Coordinates | 1920441..1922894 (-) | Length | 817 a.a. |
| NCBI ID | WP_014636516.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain SZ1908 | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1916543..1959770 | 1920441..1922894 | within | 0 |
Gene organization within MGE regions
Location: 1916543..1959770
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K8227_RS09400 (K8227_09375) | dusB | 1916543..1917547 (+) | 1005 | WP_012775355.1 | tRNA dihydrouridine synthase DusB | - |
| K8227_RS09405 (K8227_09380) | - | 1917693..1918466 (-) | 774 | WP_012027854.1 | NUDIX domain-containing protein | - |
| K8227_RS09410 (K8227_09385) | pnuC | 1918459..1919280 (-) | 822 | WP_012027855.1 | nicotinamide riboside transporter PnuC | - |
| K8227_RS09415 (K8227_09390) | - | 1919290..1920327 (-) | 1038 | WP_012028524.1 | AAA family ATPase | - |
| K8227_RS09420 (K8227_09395) | clpC | 1920441..1922894 (-) | 2454 | WP_014636516.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| K8227_RS09425 (K8227_09400) | - | 1922900..1923358 (-) | 459 | WP_012027859.1 | CtsR family transcriptional regulator | - |
| K8227_RS09430 (K8227_09405) | - | 1923508..1923846 (+) | 339 | WP_012027860.1 | thioredoxin domain-containing protein | - |
| K8227_RS09435 (K8227_09410) | - | 1923846..1924547 (+) | 702 | WP_012027861.1 | hypothetical protein | - |
| K8227_RS09440 (K8227_09415) | tsf | 1924810..1925850 (-) | 1041 | WP_012027862.1 | translation elongation factor Ts | - |
| K8227_RS09445 (K8227_09420) | rpsB | 1926006..1926782 (-) | 777 | WP_012775356.1 | 30S ribosomal protein S2 | - |
| K8227_RS09450 (K8227_09425) | - | 1927129..1927641 (-) | 513 | WP_012775452.1 | adenylate kinase | - |
| K8227_RS09460 (K8227_09435) | - | 1928295..1933373 (-) | 5079 | WP_223375654.1 | S8 family serine peptidase | - |
| K8227_RS09465 (K8227_09440) | nusG | 1933517..1934056 (-) | 540 | WP_002940254.1 | transcription termination/antitermination protein NusG | - |
| K8227_RS09470 (K8227_09445) | secE | 1934166..1934342 (-) | 177 | WP_002940255.1 | preprotein translocase subunit SecE | - |
| K8227_RS09475 (K8227_09450) | rpmG | 1934352..1934504 (-) | 153 | WP_002940258.1 | 50S ribosomal protein L33 | - |
| K8227_RS09480 (K8227_09455) | pbp2a | 1934538..1936751 (-) | 2214 | WP_012027868.1 | penicillin-binding protein PBP2A | - |
| K8227_RS09485 (K8227_09460) | - | 1936904..1937872 (+) | 969 | WP_012027869.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| K8227_RS09490 (K8227_09465) | - | 1937874..1938740 (+) | 867 | WP_012027870.1 | RluA family pseudouridine synthase | - |
| K8227_RS09495 (K8227_09470) | purR | 1938767..1939579 (-) | 813 | WP_002938438.1 | pur operon repressor | - |
| K8227_RS09500 (K8227_09475) | - | 1939681..1940547 (-) | 867 | WP_012027872.1 | aminoglycoside phosphotransferase family protein | - |
| K8227_RS09505 (K8227_09480) | - | 1940547..1941488 (-) | 942 | WP_012775359.1 | 3'-5' exoribonuclease YhaM family protein | - |
| K8227_RS09510 (K8227_09485) | - | 1941478..1942716 (-) | 1239 | WP_012027874.1 | DNA recombination protein RmuC | - |
| K8227_RS09515 (K8227_09490) | - | 1942717..1943349 (-) | 633 | WP_012027875.1 | thiamine diphosphokinase | - |
| K8227_RS09520 (K8227_09495) | rpe | 1943342..1944001 (-) | 660 | WP_012027876.1 | ribulose-phosphate 3-epimerase | - |
| K8227_RS09525 (K8227_09500) | rsgA | 1944016..1944891 (-) | 876 | WP_012027877.1 | ribosome small subunit-dependent GTPase A | - |
| K8227_RS09535 (K8227_09510) | - | 1945788..1947365 (-) | 1578 | WP_012027878.1 | ABC transporter ATP-binding protein | - |
| K8227_RS09540 (K8227_09515) | - | 1947362..1948603 (-) | 1242 | WP_014636518.1 | radical SAM protein | - |
| K8227_RS09545 (K8227_09520) | - | 1948972..1949835 (-) | 864 | WP_223375655.1 | helix-turn-helix domain-containing protein | - |
| K8227_RS09550 (K8227_09525) | - | 1950325..1952769 (-) | 2445 | WP_012027881.1 | LTA synthase family protein | - |
| K8227_RS09555 (K8227_09530) | - | 1952782..1954512 (-) | 1731 | WP_012775361.1 | membrane protein | - |
| K8227_RS09560 (K8227_09535) | rsmA | 1954877..1955749 (-) | 873 | WP_012775362.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
| K8227_RS09565 (K8227_09540) | - | 1955769..1956299 (-) | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
| K8227_RS09570 (K8227_09545) | - | 1956313..1956570 (-) | 258 | WP_211838284.1 | Txe/YoeB family addiction module toxin | - |
| K8227_RS09575 (K8227_09550) | - | 1956572..1956832 (-) | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| K8227_RS09580 (K8227_09555) | - | 1956908..1957363 (-) | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
| K8227_RS09585 (K8227_09560) | - | 1957370..1957699 (-) | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| K8227_RS09590 (K8227_09565) | - | 1957689..1957976 (-) | 288 | WP_012028535.1 | hypothetical protein | - |
| K8227_RS09595 (K8227_09570) | - | 1958074..1958442 (-) | 369 | WP_012775453.1 | hypothetical protein | - |
| K8227_RS09600 (K8227_09575) | rnmV | 1958435..1959004 (-) | 570 | WP_012775366.1 | ribonuclease M5 | - |
| K8227_RS09605 (K8227_09580) | - | 1958988..1959770 (-) | 783 | WP_012028536.1 | TatD family hydrolase | - |
Sequence
Protein
Download Length: 817 a.a. Molecular weight: 90162.56 Da Isoelectric Point: 6.3138
>NTDB_id=603854 K8227_RS09420 WP_014636516.1 1920441..1922894(-) (clpC) [Streptococcus suis strain SZ1908]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFATSRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFATSRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
Nucleotide
Download Length: 2454 bp
>NTDB_id=603854 K8227_RS09420 WP_014636516.1 1920441..1922894(-) (clpC) [Streptococcus suis strain SZ1908]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGACTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGACTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae TIGR4 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus pneumoniae Rx1 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus pneumoniae D39 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus mutans UA159 |
66.049 |
99.143 |
0.655 |
| clpC | Streptococcus thermophilus LMG 18311 |
64.706 |
99.878 |
0.646 |
| clpC | Streptococcus thermophilus LMD-9 |
64.583 |
99.878 |
0.645 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.206 |
100 |
0.493 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.526 |
99.51 |
0.443 |