Detailed information
Bioinformatically predicted
Overview
| Name | comB | Type | Machinery gene |
| Locus tag | K8P04_RS03275 | Genome accession | NZ_CP082856 |
| Coordinates | 662953..663459 (-) | Length | 168 a.a. |
| NCBI ID | WP_011272049.1 | Uniprot ID | Q4QNA7 |
| Organism | Haemophilus influenzae strain FDAARGOS_1479 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 654876..689448 | 662953..663459 | within | 0 |
Gene organization within MGE regions
Location: 654876..689448
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K8P04_RS03225 (K8P04_03200) | dsbB | 654876..655409 (+) | 534 | WP_015701641.1 | disulfide bond formation protein DsbB | - |
| K8P04_RS03230 (K8P04_03205) | glmS | 655464..657296 (-) | 1833 | WP_015701642.1 | glutamine--fructose-6-phosphate transaminase (isomerizing) | - |
| K8P04_RS03235 (K8P04_03210) | - | 657409..657681 (-) | 273 | WP_005630954.1 | HU family DNA-binding protein | - |
| K8P04_RS03240 (K8P04_03215) | - | 657821..658411 (-) | 591 | WP_015701643.1 | YjaG family protein | - |
| K8P04_RS03245 (K8P04_03220) | nudC | 658447..659241 (-) | 795 | WP_015701644.1 | NAD(+) diphosphatase | - |
| K8P04_RS03250 (K8P04_03225) | nfuA | 659308..659904 (-) | 597 | WP_005649300.1 | Fe-S biogenesis protein NfuA | - |
| K8P04_RS03255 (K8P04_03230) | - | 659980..660666 (-) | 687 | WP_015701645.1 | ComF family protein | - |
| K8P04_RS03260 (K8P04_03235) | comE | 660679..662016 (-) | 1338 | WP_015701646.1 | type IV pilus secretin PilQ family protein | Machinery gene |
| K8P04_RS03265 (K8P04_03240) | - | 662026..662438 (-) | 413 | Protein_606 | competence protein | - |
| K8P04_RS03270 (K8P04_03245) | comC | 662435..662956 (-) | 522 | WP_077643691.1 | competence protein ComC | Machinery gene |
| K8P04_RS03275 (K8P04_03250) | comB | 662953..663459 (-) | 507 | WP_011272049.1 | competence protein ComB | Machinery gene |
| K8P04_RS03280 (K8P04_03255) | comA | 663460..664257 (-) | 798 | WP_005693722.1 | competence protein A | Machinery gene |
| K8P04_RS03285 (K8P04_03260) | - | 664356..666950 (+) | 2595 | WP_077643690.1 | penicillin-binding protein 1A | - |
| K8P04_RS03290 (K8P04_03265) | - | 667027..667872 (+) | 846 | WP_015701650.1 | 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ | - |
| K8P04_RS03295 (K8P04_03270) | - | 668025..668354 (+) | 330 | WP_005629464.1 | YbaB/EbfC family nucleoid-associated protein | - |
| K8P04_RS03300 (K8P04_03275) | recR | 668487..669089 (+) | 603 | WP_005626527.1 | recombination mediator RecR | - |
| K8P04_RS03305 (K8P04_03280) | - | 669105..671060 (+) | 1956 | WP_015701651.1 | DNA topoisomerase III | - |
| K8P04_RS03310 (K8P04_03285) | secG | 671169..671510 (+) | 342 | WP_005649335.1 | preprotein translocase subunit SecG | - |
| K8P04_RS03320 (K8P04_03295) | - | 671888..673114 (+) | 1227 | WP_015701652.1 | integrase arm-type DNA-binding domain-containing protein | - |
| K8P04_RS03325 (K8P04_03300) | - | 673286..675055 (-) | 1770 | WP_015701653.1 | phage/plasmid primase, P4 family | - |
| K8P04_RS03330 (K8P04_03305) | - | 675084..675434 (-) | 351 | WP_015701654.1 | hypothetical protein | - |
| K8P04_RS03335 (K8P04_03310) | - | 675427..676065 (-) | 639 | WP_015701655.1 | hypothetical protein | - |
| K8P04_RS03340 (K8P04_03315) | - | 676052..676258 (-) | 207 | WP_015701656.1 | hypothetical protein | - |
| K8P04_RS03345 (K8P04_03320) | - | 676248..676448 (-) | 201 | WP_015701657.1 | hypothetical protein | - |
| K8P04_RS03350 (K8P04_03325) | - | 676438..676809 (-) | 372 | WP_015701658.1 | hypothetical protein | - |
| K8P04_RS03355 (K8P04_03330) | - | 676802..677731 (-) | 930 | WP_015701659.1 | host cell division inhibitor Icd-like protein | - |
| K8P04_RS03360 (K8P04_03335) | - | 677898..678209 (-) | 312 | WP_015701660.1 | hypothetical protein | - |
| K8P04_RS03365 (K8P04_03340) | - | 678221..678430 (-) | 210 | WP_015701661.1 | AlpA family transcriptional regulator | - |
| K8P04_RS03370 (K8P04_03345) | - | 678603..679565 (-) | 963 | WP_050792024.1 | hypothetical protein | - |
| K8P04_RS03375 (K8P04_03350) | - | 679662..680048 (-) | 387 | WP_015701663.1 | hypothetical protein | - |
| K8P04_RS03380 (K8P04_03355) | - | 680289..680573 (-) | 285 | WP_015701664.1 | hypothetical protein | - |
| K8P04_RS03385 (K8P04_03360) | - | 680570..682237 (-) | 1668 | WP_015701665.1 | terminase large subunit | - |
| K8P04_RS03390 (K8P04_03365) | - | 682244..682612 (-) | 369 | WP_015701666.1 | phage terminase small subunit P27 family | - |
| K8P04_RS03395 (K8P04_03370) | - | 682809..683195 (-) | 387 | WP_015701667.1 | HNH endonuclease signature motif containing protein | - |
| K8P04_RS03400 (K8P04_03375) | - | 683210..683524 (-) | 315 | WP_015701668.1 | head-tail connector protein | - |
| K8P04_RS03405 (K8P04_03380) | - | 683511..683855 (-) | 345 | WP_041175043.1 | phage head closure protein | - |
| K8P04_RS03410 (K8P04_03385) | - | 683839..685071 (-) | 1233 | WP_041175044.1 | phage portal protein | - |
| K8P04_RS03415 (K8P04_03390) | - | 685073..685639 (-) | 567 | WP_015701671.1 | HK97 family phage prohead protease | - |
| K8P04_RS03420 (K8P04_03395) | - | 685693..686880 (-) | 1188 | WP_015701672.1 | phage major capsid protein | - |
| K8P04_RS03425 (K8P04_03400) | - | 687778..689448 (-) | 1671 | WP_015701673.1 | fructose-specific PTS transporter subunit EIIC | - |
Sequence
Protein
Download Length: 168 a.a. Molecular weight: 19697.54 Da Isoelectric Point: 7.4684
>NTDB_id=603083 K8P04_RS03275 WP_011272049.1 662953..663459(-) (comB) [Haemophilus influenzae strain FDAARGOS_1479]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQTSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQTSFEQLNQQLHKTTMQIDQLRSAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK
Nucleotide
Download Length: 507 bp
>NTDB_id=603083 K8P04_RS03275 WP_011272049.1 662953..663459(-) (comB) [Haemophilus influenzae strain FDAARGOS_1479]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAAGCGCAGCAAA
CATCTTTTGAACAACTTAATCAGCAACTTCACAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGCTTGGAAGGTAACGCACAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAAGCGCAGCAAA
CATCTTTTGAACAACTTAATCAGCAACTTCACAAAACTACCATGCAAATTGATCAGTTACGCAGTGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCCAATAACTTAAGCTTGGAAGGTAACGCACAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB | Haemophilus influenzae 86-028NP |
100 |
100 |
1 |
| comB | Haemophilus influenzae Rd KW20 |
98.81 |
100 |
0.988 |