Detailed information NTG0603033

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: K8O86_RS17555
• Genome accession: NZ_CP082850
• Coordinates: 4006343..4008565 (+)
• Length: 740 a.a.
• NCBI ID: WP_003635596.1
• Uniprot ID: D3HKP4
• Organism: Legionella longbeachae strain FDAARGOS_1481
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4001343..4013565

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8O86_RS17530 (K8O86_17470)	-	4001584..4002222 (-)	639	WP_003635606.1	hypothetical protein	-
K8O86_RS17535 (K8O86_17475)	-	4002464..4003489 (-)	1026	WP_003635604.1	PotD/PotF family extracellular solute-binding protein	-
K8O86_RS17540 (K8O86_17480)	-	4003486..4004253 (-)	768	WP_003635601.1	ABC transporter permease subunit	-
K8O86_RS17545 (K8O86_17485)	-	4004250..4005074 (-)	825	WP_003635599.1	ABC transporter permease	-
K8O86_RS17550 (K8O86_17490)	potA	4005064..4006158 (-)	1095	WP_003635598.1	spermidine/putrescine ABC transporter ATP-binding protein PotA	-
K8O86_RS17555 (K8O86_17495)	comEC	4006343..4008565 (+)	2223	WP_003635596.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
K8O86_RS17560 (K8O86_17500)	-	4008675..4009724 (+)	1050	WP_003635594.1	bifunctional transcriptional activator/DNA repair enzyme AdaA	-
K8O86_RS17565 (K8O86_17505)	-	4010081..4010308 (-)	228	WP_172622913.1	hypothetical protein	-
K8O86_RS17570 (K8O86_17510)	-	4010734..4011549 (-)	816	WP_003635585.1	mechanosensitive ion channel family protein	-
K8O86_RS17575 (K8O86_17515)	-	4011872..4012195 (-)	324	WP_003635583.1	hypothetical protein	-
K8O86_RS17580 (K8O86_17520)	-	4012530..4012916 (+)	387	WP_003635579.1	group III truncated hemoglobin	-
K8O86_RS17585 (K8O86_17525)	cydP	4012910..4013080 (+)	171	WP_003635577.1	cytochrome oxidase putative small subunit CydP	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 83609.84 Da
• Isoelectric Point: 9.6797

>NTDB_id=603033 K8O86_RS17555 WP_003635596.1 4006343..4008565(+) (comEC) [Legionella longbeachae strain FDAARGOS_1481]
MEIFCFFIGILYRYTLHGLLPILILFIFFIIPRYANILFFLLGIFIATVHQSQNLPKGLPDVEVIPQVSIQGTIASIPLQ
SPSKTLFLLALEQYDNHPAQGIIQLSWYNKAPKIHVGQRWKFKVKLKKPRNYLNPGSMDYVRSLATRHILWTGYIHSRGN
KQLPKVPSSFNWLELREQLSEQLGLLAPDQKTAGIVEALALNITTHIDQKSWDLFRRTGTTHLFGISGEHIALISGIIYW
LLRWIWTRSSRLCLRIPAPHIASMGGLLAASGYAFLAGFAPPVQRALIGCFFYTLYSLGYQRFTPWQVWRYALCGVLLIE
PHAVFMQGFYFSFLAVACLLLTQQRWRLKGYKASLALQLSCLIGLMPLTLYWYAYGSINGFIANLFAIPLVGLLIVPLSL
MTMTVSSLSIAKILMKAVSLLITLLFKGLSLSEYLAALNINCPIYSIELALVLIGALLMWVLLPTKPFQWIAMLWLLLPF
FPPRTIIQAGEAKIDVLDVGQGLAVAIRTQHHVLLYDTGDRFFQGNDLGKMVILPYLNTLGIKKIDTIVVSHPDKDHLGG
LKSLEKEIPVERLLVNEPHFYHRGLKCHDYPPWQWDGVSFRFLPIKIPLRGKNNSSCILQIETHAGRMLLAGDIEKIAED
YLVQTYGNILESDVLLVPHHGSKTSSSYRFLLEVAPLYAIASLGFDNRFHFPHDKTLANMKKLNIPFYRTDTCGMVQITL
PAQGALTHPTCFSGQRLQPV

Nucleotide

• Length: 2223 bp

>NTDB_id=603033 K8O86_RS17555 WP_003635596.1 4006343..4008565(+) (comEC) [Legionella longbeachae strain FDAARGOS_1481]
ATGGAAATTTTTTGCTTTTTTATAGGCATATTGTATCGATATACCTTACACGGATTATTGCCTATACTTATTTTATTTAT
TTTTTTCATTATTCCCAGGTATGCGAATATCCTGTTTTTTCTTTTAGGCATCTTCATCGCGACTGTGCACCAATCTCAAA
ATTTACCAAAAGGATTACCCGATGTTGAAGTAATACCCCAAGTCAGCATCCAAGGAACAATTGCATCTATTCCGCTCCAA
AGTCCATCTAAGACACTCTTTTTATTGGCTTTAGAACAATACGACAATCATCCAGCACAAGGGATAATACAATTATCATG
GTATAACAAAGCCCCCAAAATCCATGTAGGGCAACGATGGAAATTTAAAGTGAAATTGAAAAAGCCAAGAAATTATCTAA
ATCCAGGGAGTATGGATTATGTACGTTCACTCGCAACACGCCATATATTGTGGACTGGATATATTCATTCTAGAGGAAAT
AAGCAACTCCCAAAAGTCCCCTCATCTTTCAATTGGCTAGAACTAAGGGAACAATTAAGCGAGCAACTCGGCTTGTTGGC
ACCTGATCAAAAAACCGCTGGAATTGTAGAGGCTTTAGCTTTAAATATAACAACCCATATTGACCAGAAAAGCTGGGATT
TGTTTAGACGTACTGGCACAACCCATTTATTTGGTATTTCAGGTGAACATATCGCCTTAATTTCAGGTATTATTTATTGG
TTACTCCGTTGGATATGGACTCGAAGCTCTCGTCTTTGCTTACGCATTCCAGCCCCTCATATTGCAAGTATGGGTGGCCT
TTTGGCTGCATCAGGATATGCGTTTTTAGCAGGTTTTGCACCTCCTGTCCAAAGGGCACTTATCGGATGTTTTTTTTATA
CCCTTTATAGCTTGGGCTACCAGCGTTTTACTCCATGGCAAGTATGGCGCTATGCTCTATGTGGTGTCTTATTGATTGAA
CCACATGCCGTATTTATGCAAGGATTCTATTTTTCTTTTCTTGCAGTAGCATGCTTGCTCTTAACACAACAACGCTGGCG
TTTAAAAGGATATAAAGCCTCTTTAGCCCTACAGTTAAGCTGTTTAATTGGGTTAATGCCCCTAACCTTATATTGGTATG
CTTATGGCTCAATTAATGGATTTATTGCAAACCTTTTCGCTATACCTTTGGTGGGATTACTCATTGTTCCGTTGTCATTA
ATGACAATGACGGTCAGCTCTTTAAGCATTGCAAAGATACTAATGAAGGCCGTTTCTTTACTCATTACCCTATTGTTTAA
AGGGCTATCCTTGTCAGAATATTTAGCTGCTCTAAATATTAATTGCCCCATTTATTCTATAGAACTGGCTCTTGTTCTAA
TTGGAGCTTTATTGATGTGGGTTTTACTACCCACTAAACCTTTTCAATGGATCGCGATGCTTTGGTTATTGCTCCCGTTT
TTTCCACCGCGAACAATCATTCAAGCAGGCGAAGCCAAAATAGATGTTTTGGACGTAGGGCAAGGCTTGGCTGTTGCGAT
TCGAACGCAACACCATGTATTGCTTTATGATACAGGAGATCGTTTCTTTCAAGGAAATGATTTAGGGAAAATGGTTATTT
TGCCTTATCTTAACACTTTGGGTATCAAAAAAATTGATACCATAGTTGTGAGCCATCCTGATAAAGATCATCTTGGAGGA
CTTAAATCACTGGAAAAAGAAATACCAGTAGAGAGGCTATTAGTCAATGAGCCTCATTTCTATCATCGTGGTTTAAAATG
TCATGATTATCCACCATGGCAATGGGACGGTGTTTCGTTCCGTTTTCTGCCAATAAAAATTCCCCTTAGAGGAAAAAACA
ACAGTTCTTGCATTTTACAAATAGAAACACATGCAGGACGGATGCTCTTAGCTGGCGATATTGAAAAAATAGCTGAAGAT
TATCTGGTGCAGACTTATGGCAATATTCTTGAATCAGATGTGCTGCTTGTTCCTCATCATGGCAGTAAAACTTCATCATC
CTACAGATTCTTATTAGAAGTTGCTCCGCTCTATGCTATAGCCTCCCTGGGCTTTGATAATCGCTTTCACTTTCCCCATG
ACAAGACTTTAGCAAACATGAAAAAACTGAATATCCCTTTTTACAGAACAGATACTTGTGGCATGGTACAGATTACTTTG
CCTGCCCAAGGAGCACTCACTCATCCCACTTGCTTTAGTGGACAGAGGTTACAACCCGTGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (201-465)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-676)

• Domain of unknown function (DUF4131) (DUF4131) (16-157)

3D structure

• AlphaFold DB: D3HKP4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Legionella pneumophila strain Lp02	64.305	99.189	0.638
comEC	Legionella pneumophila strain ERS1305867	63.81	99.324	0.634