Detailed information NTG0602554

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: K8B76_RS08460
• Genome accession: NZ_CP082820
• Coordinates: 1711551..1712618 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159564.1
• Uniprot ID: A0A6I3U7F3
• Organism: Streptococcus pneumoniae strain SCAID PHRX1-2021
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1706551..1717618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8B76_RS08445 (K8B76_08445)	treR	1708340..1709050 (+)	711	WP_000760675.1	trehalose operon repressor	Regulator
K8B76_RS08450 (K8B76_08450)	-	1709205..1710539 (+)	1335	Protein_1693	ISL3 family transposase	-
K8B76_RS08455 (K8B76_08455)	amiF	1710614..1711540 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
K8B76_RS08460 (K8B76_08460)	amiE	1711551..1712618 (-)	1068	WP_000159564.1	ABC transporter ATP-binding protein	Regulator
K8B76_RS08465 (K8B76_08465)	amiD	1712627..1713553 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
K8B76_RS08470 (K8B76_08470)	amiC	1713553..1715049 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
K8B76_RS08475 (K8B76_08475)	amiA3	1715116..1717095 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39520.11 Da
• Isoelectric Point: 4.8727

>NTDB_id=602554 K8B76_RS08460 WP_000159564.1 1711551..1712618(-) (amiE) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRSQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=602554 K8B76_RS08460 WP_000159564.1 1711551..1712618(-) (amiE) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTAGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A6I3U7F3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538