Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   NEE09_RS10125 Genome accession   NZ_CP099641
Coordinates   1966821..1967261 (+) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain ATCC 700671     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1961821..1972261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NEE09_RS10100 ribE 1961863..1962498 (+) 636 WP_000493842.1 riboflavin synthase -
  NEE09_RS10105 - 1962518..1963723 (+) 1206 WP_001818099.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  NEE09_RS10110 ribE 1963724..1964191 (+) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  NEE09_RS10115 hexB 1964516..1966465 (-) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  NEE09_RS10120 - 1966608..1966733 (+) 126 WP_001813544.1 hypothetical protein -
  NEE09_RS10125 brsR 1966821..1967261 (+) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  NEE09_RS10130 - 1967258..1967716 (+) 459 WP_000745054.1 DUF3021 domain-containing protein -
  NEE09_RS10135 - 1968026..1969288 (+) 1263 WP_000075793.1 NRAMP family divalent metal transporter -
  NEE09_RS10140 nrdI 1969581..1970051 (-) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  NEE09_RS10145 - 1970129..1970662 (-) 534 WP_000729029.1 hypothetical protein -
  NEE09_RS10150 - 1970714..1972000 (-) 1287 WP_000278878.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=602549 NEE09_RS10125 WP_000861956.1 1966821..1967261(+) (brsR) [Streptococcus pneumoniae strain ATCC 700671]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=602549 NEE09_RS10125 WP_000861956.1 1966821..1967261(+) (brsR) [Streptococcus pneumoniae strain ATCC 700671]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363