Detailed information NTG0602506

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: K8B78_RS09785
• Genome accession: NZ_CP082815
• Coordinates: 2007443..2008486 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SCAID WND1-2021 (598)
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2002443..2013486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8B78_RS09755 (K8B78_09755)	-	2002864..2004120 (-)	1257	WP_001793983.1	aminopeptidase	-
K8B78_RS09760 (K8B78_09760)	-	2004123..2004323 (-)	201	WP_000180460.1	DUF1128 family protein	-
K8B78_RS09765 (K8B78_09765)	-	2004470..2004934 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
K8B78_RS09770 (K8B78_09770)	-	2004941..2005216 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
K8B78_RS09775 (K8B78_09775)	-	2005494..2006711 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
K8B78_RS09780 (K8B78_09780)	vraR	2006824..2007453 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
K8B78_RS09785 (K8B78_09785)	vraS	2007443..2008486 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
K8B78_RS09790 (K8B78_09790)	liaF	2008483..2009184 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
K8B78_RS09795 (K8B78_09795)	-	2009199..2009585 (-)	387	WP_001110178.1	hypothetical protein	-
K8B78_RS09800 (K8B78_09800)	map	2009802..2010560 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
K8B78_RS09805 (K8B78_09805)	-	2011260..2012246 (+)	987	WP_001014423.1	FUSC family protein	-
K8B78_RS09810 (K8B78_09810)	-	2012435..2012848 (-)	414	WP_001643743.1	hypothetical protein	-
K8B78_RS09815 (K8B78_09815)	-	2012877..2012987 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=602506 K8B78_RS09785 WP_001017131.1 2007443..2008486(-) (vraS) [Staphylococcus aureus strain SCAID WND1-2021 (598)]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=602506 K8B78_RS09785 WP_001017131.1 2007443..2008486(-) (vraS) [Staphylococcus aureus strain SCAID WND1-2021 (598)]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1