Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   K8B68_RS09920 Genome accession   NZ_CP082813
Coordinates   2022861..2023577 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain SCAID OTT1-2021 (597/2)     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2017861..2028577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8B68_RS09890 (K8B68_09890) - 2018076..2018702 (+) 627 WP_000522375.1 nitroreductase family protein -
  K8B68_RS09895 (K8B68_09895) - 2019063..2019848 (+) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  K8B68_RS13720 hld 2020449..2020529 (-) 81 WP_000046022.1 delta-hemolysin -
  K8B68_RS09905 (K8B68_09905) agrB 2020819..2021388 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  K8B68_RS09910 (K8B68_09910) agrD 2021385..2021525 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  K8B68_RS09915 (K8B68_09915) agrC 2021550..2022842 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  K8B68_RS09920 (K8B68_09920) agrA 2022861..2023577 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  K8B68_RS09925 (K8B68_09925) - 2023649..2023756 (+) 108 WP_031785433.1 hypothetical protein -
  K8B68_RS09930 (K8B68_09930) - 2023946..2024905 (-) 960 WP_001253295.1 carbohydrate kinase family protein -
  K8B68_RS09935 (K8B68_09935) - 2024902..2026386 (-) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  K8B68_RS09940 (K8B68_09940) - 2026535..2027485 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=602466 K8B68_RS09920 WP_000688492.1 2022861..2023577(+) (agrA) [Staphylococcus aureus strain SCAID OTT1-2021 (597/2)]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=602466 K8B68_RS09920 WP_000688492.1 2022861..2023577(+) (agrA) [Staphylococcus aureus strain SCAID OTT1-2021 (597/2)]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1