Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   NHB12_RS10670 Genome accession   NZ_CP099576
Coordinates   2128940..2129653 (+) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain MRSA1369     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2123940..2134653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NHB12_RS10610 (NHB12_10610) - 2125309..2125572 (-) 264 WP_001205732.1 hypothetical protein -
  NHB12_RS10615 (NHB12_10615) - 2125581..2125841 (-) 261 WP_000291513.1 DUF1108 family protein -
  NHB12_RS10620 (NHB12_10620) - 2125822..2126141 (-) 320 Protein_2059 DUF2482 family protein -
  NHB12_RS10625 (NHB12_10625) - 2126236..2126397 (-) 162 WP_001285960.1 DUF1270 domain-containing protein -
  NHB12_RS10630 (NHB12_10630) - 2126394..2126714 (-) 321 WP_001120199.1 DUF771 domain-containing protein -
  NHB12_RS10635 (NHB12_10635) - 2126773..2127003 (+) 231 WP_000549548.1 hypothetical protein -
  NHB12_RS10640 (NHB12_10640) - 2127000..2127176 (-) 177 WP_001001356.1 hypothetical protein -
  NHB12_RS10645 (NHB12_10645) - 2127192..2127944 (-) 753 WP_001148642.1 phage antirepressor KilAC domain-containing protein -
  NHB12_RS10650 (NHB12_10650) - 2127995..2128324 (+) 330 WP_000180411.1 hypothetical protein -
  NHB12_RS10655 (NHB12_10655) - 2128313..2128528 (-) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  NHB12_RS10660 (NHB12_10660) - 2128544..2128807 (-) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  NHB12_RS10665 (NHB12_10665) - 2128804..2128977 (-) 174 WP_001801500.1 hypothetical protein -
  NHB12_RS10670 (NHB12_10670) irvR 2128940..2129653 (+) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  NHB12_RS10675 (NHB12_10675) - 2129669..2130601 (+) 933 WP_000759682.1 exonuclease domain-containing protein -
  NHB12_RS10680 (NHB12_10680) - 2130607..2130948 (+) 342 WP_000591749.1 hypothetical protein -
  NHB12_RS10685 (NHB12_10685) - 2131152..2131334 (+) 183 WP_000705246.1 hypothetical protein -
  NHB12_RS10690 (NHB12_10690) - 2131412..2132125 (+) 714 WP_253719056.1 type II toxin-antitoxin system PemK/MazF family toxin -
  NHB12_RS10695 (NHB12_10695) - 2132316..2133353 (+) 1038 WP_000857199.1 site-specific integrase -
  NHB12_RS10700 (NHB12_10700) sph 2133404..2134234 (+) 831 Protein_2075 sphingomyelin phosphodiesterase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=602262 NHB12_RS10670 WP_001031454.1 2128940..2129653(+) (irvR) [Staphylococcus aureus strain MRSA1369]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=602262 NHB12_RS10670 WP_001031454.1 2128940..2129653(+) (irvR) [Staphylococcus aureus strain MRSA1369]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401