Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   K7G42_RS08455 Genome accession   NZ_CP082783
Coordinates   1580348..1582633 (+) Length   761 a.a.
NCBI ID   WP_003108178.1    Uniprot ID   -
Organism   Streptococcus parauberis strain KRS02083     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1575348..1587633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K7G42_RS08425 (K7G42_08365) - 1575415..1575549 (-) 135 WP_003107303.1 FeoB-associated Cys-rich membrane protein -
  K7G42_RS08430 (K7G42_08370) feoB 1575549..1577702 (-) 2154 WP_003108179.1 ferrous iron transport protein B -
  K7G42_RS08435 (K7G42_08375) - 1577720..1578178 (-) 459 WP_003105762.1 ferrous iron transport protein A -
  K7G42_RS08440 (K7G42_08380) - 1578290..1579024 (-) 735 WP_003102516.1 amino acid ABC transporter ATP-binding protein -
  K7G42_RS08445 (K7G42_08385) - 1579021..1579710 (-) 690 WP_003103587.1 amino acid ABC transporter permease -
  K7G42_RS08450 (K7G42_08390) - 1579838..1580068 (-) 231 WP_003105222.1 DUF1797 family protein -
  K7G42_RS08455 (K7G42_08395) clpE 1580348..1582633 (+) 2286 WP_003108178.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  K7G42_RS08460 (K7G42_08400) - 1582752..1583201 (+) 450 WP_003103112.1 NUDIX hydrolase -
  K7G42_RS08465 (K7G42_08405) - 1583250..1583558 (+) 309 WP_003108176.1 DUF1827 family protein -
  K7G42_RS08470 (K7G42_08410) ileS 1583624..1586419 (-) 2796 WP_003108175.1 isoleucine--tRNA ligase -
  K7G42_RS08475 (K7G42_08415) - 1586676..1587440 (-) 765 WP_003107309.1 DivIVA domain-containing protein -

Sequence

Protein


Download         Length: 761 a.a.        Molecular weight: 84871.05 Da        Isoelectric Point: 4.9368

>NTDB_id=602213 K7G42_RS08455 WP_003108178.1 1580348..1582633(+) (clpE) [Streptococcus parauberis strain KRS02083]
MLCQNCQLNEASIHLYTNVNGKQKQIDLCQNCYQIMKTDANNSILGGIGSRSEKKQDPMNPFFDDFFGDLNNFRSFGNLP
NTPPTQAGGSGGNNGKIPNQQGSRNQNAQATQQPKGLLEEFGINVTEIARKGGIDPVIGRDEEITRVIEILNRRTKNNPV
LIGEPGVGKTAVVEGLAQKIVDSDVPYKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRQDVILFIDEIHEIV
GAGNAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQTKYEDYHHVK
YTDDAIIAAATLSNRYIQDRFLPDKAIDLLDEAGSKLNLTLTFVDPKEIDQRLVEAENLKAQATRDEDYERAAYFRDQII
KYKELQKQKVDEEDTPIITEKTIEGILEDKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGT
PNRPIGSFLFVGPTGVGKTELSKQLAIELFGTADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSL
ILLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTSTNEASVGFGAAREGRTSSVLGQLTNFFNPE
FMNRFDGIIEFQTLSKDNLLHIVDLMLEDVNNRLSQNGLHLDVTNKVKEKLVDLGYNPKMGARPLRRTIQDYIEDAITDF
YLENPSEKELKAMMTSNGNIIIKSAKKSNSPVEDQTKSYEN

Nucleotide


Download         Length: 2286 bp        

>NTDB_id=602213 K7G42_RS08455 WP_003108178.1 1580348..1582633(+) (clpE) [Streptococcus parauberis strain KRS02083]
ATGCTCTGTCAGAATTGTCAATTAAATGAAGCTTCAATCCATTTATATACCAATGTTAATGGGAAACAAAAGCAAATTGA
TTTATGTCAAAATTGCTATCAAATAATGAAAACGGATGCGAATAATTCAATATTAGGGGGAATTGGTTCGCGTTCAGAAA
AAAAACAAGACCCAATGAATCCATTCTTTGATGACTTTTTCGGTGATTTGAATAACTTTCGATCTTTCGGAAATCTACCT
AATACTCCTCCAACTCAGGCAGGTGGAAGCGGTGGAAATAATGGGAAAATTCCTAACCAACAGGGCTCTCGTAATCAAAA
TGCACAAGCTACTCAACAGCCTAAAGGCTTACTAGAAGAGTTTGGTATCAATGTTACGGAAATTGCCCGTAAAGGAGGTA
TTGACCCTGTTATAGGTCGTGACGAAGAGATTACACGTGTCATTGAAATTCTCAATCGTCGTACAAAGAATAATCCAGTT
CTAATTGGCGAACCCGGTGTTGGTAAAACTGCTGTCGTTGAAGGTTTAGCTCAAAAAATTGTGGACAGTGATGTCCCATA
TAAACTTCAAGGTAAACAAGTGATTCGTTTAGATGTTGTTAGTTTAGTCCAAGGAACTGGAATCCGTGGTCAATTTGAAG
AACGAATGCAAAAACTGATGGAAGAAATAAGAAACCGTCAAGATGTTATCTTATTCATTGATGAAATTCACGAAATTGTT
GGAGCCGGTAATGCAGGTGATGGCAACATGGACGCTGGAAATATCTTAAAACCTGCACTTGCTCGTGGTGAATTACAGTT
AGTTGGTGCTACTACACTTAATGAGTATCGAATTATTGAGAAAGATGCCGCCTTAGAACGACGTATGCAACCTGTTAAGG
TTGATGAGCCTTCTGTTGAAGAAACAATTACCATCTTAAAAGGGATCCAGACTAAGTACGAAGATTATCATCATGTTAAG
TATACAGATGATGCTATCATTGCTGCTGCGACACTTTCTAATCGATATATTCAAGATCGCTTCCTTCCAGACAAAGCAAT
TGACTTACTCGATGAAGCCGGCTCAAAATTGAACTTGACGTTAACTTTTGTTGATCCAAAAGAAATAGATCAACGTCTTG
TCGAAGCCGAAAACTTAAAAGCGCAGGCTACACGAGATGAAGACTATGAGCGCGCAGCTTATTTCCGCGACCAAATTATC
AAATATAAAGAGTTACAAAAGCAAAAAGTTGATGAAGAAGATACCCCAATCATTACTGAGAAAACAATTGAAGGTATCTT
AGAGGACAAAACCAATATCCCTGTGGGTGATTTGAAAGAAAAAGAACAATCACAATTGATTCACCTGGCTGAAGACTTGA
AGAGTCATGTCATTGGTCAAGACGATGCTGTTGATAAAATTGCTAAAGCTATTCGTCGTAACCGGGTCGGTCTAGGTACG
CCAAATCGACCAATCGGTTCATTCTTATTCGTGGGTCCTACAGGTGTAGGGAAAACTGAGTTATCTAAGCAATTAGCAAT
TGAACTTTTTGGTACAGCCGATAATATGATTCGTTTTGATATGTCAGAGTACATGGAAAAACATGCCGTTGCTAAGTTGG
TTGGTGCCCCTCCTGGCTATGTCGGATATGAGGAAGCCGGTCAATTAACGGAAAAAGTCCGTCGCAATCCTTATTCACTC
ATTTTGCTGGATGAAATTGAAAAAGCTCACCCTGATGTTATGCACATGTTCCTTCAAGTTTTAGACGATGGTCGTTTGAC
TGATGGGCAAGGCCGGACAGTTAGCTTTAAAGATACCATCATCATTATGACTTCTAATGCCGGGACAAGTACTAATGAAG
CCTCTGTCGGATTTGGGGCAGCCCGCGAAGGACGAACAAGTTCAGTTCTGGGACAATTAACAAATTTCTTTAATCCAGAA
TTTATGAACCGTTTTGATGGTATTATTGAATTCCAAACATTAAGCAAAGATAATCTATTACATATTGTTGATTTGATGTT
AGAAGATGTCAACAATCGCCTCTCTCAAAATGGTCTTCACCTTGATGTGACCAATAAAGTTAAAGAGAAATTAGTCGATC
TTGGTTATAATCCAAAAATGGGTGCTCGTCCATTAAGAAGAACTATTCAAGATTACATTGAAGATGCTATTACTGATTTC
TACTTGGAAAATCCAAGTGAAAAAGAGCTTAAAGCAATGATGACTAGTAATGGAAATATCATTATTAAATCAGCAAAAAA
ATCTAATTCACCTGTGGAAGATCAAACCAAGTCTTACGAAAATTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(654-728)

AAA lid domain (AAA_lid_9)

(298-395)

ATPase family associated with various cellular activities (AAA) (AAA)

(160-280)

AAA domain (Cdc48 subfamily) (AAA_2)

(483-646)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.079

99.869

0.84
  clpE Streptococcus pneumoniae Rx1

83.69

98.292

0.823
  clpE Streptococcus pneumoniae D39

83.69

98.292

0.823
  clpE Streptococcus pneumoniae R6

83.69

98.292

0.823
  clpE Streptococcus pneumoniae TIGR4

83.556

98.292

0.821
  clpC Lactococcus lactis subsp. cremoris KW2

74.735

99.343

0.742
  clpC Bacillus subtilis subsp. subtilis str. 168

51.613

85.545

0.442
  clpC Streptococcus pneumoniae D39

46.635

83.968

0.392
  clpC Streptococcus pneumoniae Rx1

46.635

83.968

0.392
  clpC Streptococcus pneumoniae TIGR4

46.635

83.968

0.392
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.72

82.129

0.384
  clpC Streptococcus mutans UA159

47.317

80.815

0.382
  clpC Streptococcus thermophilus LMD-9

46.24

82.129

0.38
  clpC Streptococcus thermophilus LMG 18311

45.92

82.129

0.377