Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   LPT18_RS13200 Genome accession   NZ_CP099508
Coordinates   2701550..2702263 (-) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain S82     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2696550..2707263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPT18_RS13170 (LPT18_13170) sph 2696929..2697759 (-) 831 Protein_2559 sphingomyelin phosphodiesterase -
  LPT18_RS13175 (LPT18_13175) - 2697810..2698847 (-) 1038 WP_000857200.1 site-specific integrase -
  LPT18_RS13180 (LPT18_13180) - 2699040..2699744 (-) 705 WP_017804779.1 type II toxin-antitoxin system PemK/MazF family toxin -
  LPT18_RS13185 (LPT18_13185) - 2699884..2700051 (-) 168 WP_000694771.1 hypothetical protein -
  LPT18_RS13190 (LPT18_13190) - 2700255..2700596 (-) 342 WP_000591749.1 hypothetical protein -
  LPT18_RS13195 (LPT18_13195) - 2700602..2701534 (-) 933 WP_096002309.1 exonuclease domain-containing protein -
  LPT18_RS13200 (LPT18_13200) irvR 2701550..2702263 (-) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  LPT18_RS13205 (LPT18_13205) - 2702226..2702400 (+) 175 Protein_2566 transcriptional regulator -
  LPT18_RS13210 (LPT18_13210) - 2702397..2702660 (+) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  LPT18_RS13215 (LPT18_13215) - 2702676..2702891 (+) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  LPT18_RS13220 (LPT18_13220) - 2702880..2703209 (-) 330 WP_000128907.1 hypothetical protein -
  LPT18_RS13225 (LPT18_13225) - 2703260..2704012 (+) 753 WP_096002308.1 phage antirepressor KilAC domain-containing protein -
  LPT18_RS13230 (LPT18_13230) - 2704025..2704285 (+) 261 WP_000435343.1 hypothetical protein -
  LPT18_RS13235 (LPT18_13235) - 2704309..2704464 (-) 156 Protein_2572 hypothetical protein -
  LPT18_RS13240 (LPT18_13240) - 2704519..2704845 (+) 327 WP_001025595.1 hypothetical protein -
  LPT18_RS13245 (LPT18_13245) - 2704842..2704940 (+) 99 Protein_2574 hypothetical protein -
  LPT18_RS13250 (LPT18_13250) - 2705090..2705413 (+) 324 WP_001120201.1 DUF771 domain-containing protein -
  LPT18_RS13255 (LPT18_13255) - 2705410..2705571 (+) 162 WP_000048129.1 DUF1270 family protein -
  LPT18_RS13260 (LPT18_13260) - 2705666..2705968 (+) 303 WP_000165371.1 DUF2482 family protein -
  LPT18_RS13265 (LPT18_13265) - 2705973..2706233 (+) 261 WP_000291510.1 DUF1108 family protein -
  LPT18_RS13270 (LPT18_13270) - 2706242..2706505 (+) 264 WP_001205732.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=602128 LPT18_RS13200 WP_001031454.1 2701550..2702263(-) (irvR) [Staphylococcus aureus strain S82]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=602128 LPT18_RS13200 WP_001031454.1 2701550..2702263(-) (irvR) [Staphylococcus aureus strain S82]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401