Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA/pilA1   Type   Machinery gene
Locus tag   K7H19_RS06150 Genome accession   NZ_CP082323
Coordinates   1160338..1160808 (+) Length   156 a.a.
NCBI ID   WP_011228522.1    Uniprot ID   Q5SIZ8
Organism   Thermus thermophilus strain N-1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1155338..1165808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K7H19_RS06130 (K7H19_06130) ilvC 1155838..1156851 (-) 1014 WP_011173279.1 ketol-acid reductoisomerase -
  K7H19_RS06135 (K7H19_06135) ilvN 1156848..1157360 (-) 513 WP_011173280.1 acetolactate synthase small subunit -
  K7H19_RS06140 (K7H19_06140) ilvB 1157357..1159045 (-) 1689 WP_011228519.1 biosynthetic-type acetolactate synthase large subunit -
  K7H19_RS06145 (K7H19_06145) - 1159200..1160180 (-) 981 WP_011228521.1 YpdA family putative bacillithiol disulfide reductase -
  K7H19_RS06150 (K7H19_06150) pilA/pilA1 1160338..1160808 (+) 471 WP_011228522.1 GspH/FimT family protein Machinery gene
  K7H19_RS06155 (K7H19_06155) - 1160863..1161330 (+) 468 WP_011228523.1 GspH/FimT family protein -
  K7H19_RS06160 (K7H19_06160) - 1161356..1161688 (+) 333 WP_224065211.1 prepilin -
  K7H19_RS06165 (K7H19_06165) - 1161685..1162395 (+) 711 WP_011228525.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  K7H19_RS06170 (K7H19_06170) - 1162409..1163908 (+) 1500 WP_011228526.1 PilX N-terminal domain-containing pilus assembly protein -
  K7H19_RS06175 (K7H19_06175) - 1164181..1164549 (+) 369 WP_011228527.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  K7H19_RS06180 (K7H19_06180) - 1164608..1164979 (+) 372 WP_011228528.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 16937.73 Da        Isoelectric Point: 11.7108

>NTDB_id=601474 K7H19_RS06150 WP_011228522.1 1160338..1160808(+) (pilA/pilA1) [Thermus thermophilus strain N-1]
MTRRGLTLLELLLVLGILGVFLGLALPLLSPNRLALDQAARSLATQVTRARLEAIRRNAFVGLQVFTEGAGGYLLFVDQN
ANRRYDPGEEFGATRFGQGNWARVRLDPEKSALGNMPLLFDPRGIPAKPITATLVLTSGGATRKVVISQQGRARLE

Nucleotide


Download         Length: 471 bp        

>NTDB_id=601474 K7H19_RS06150 WP_011228522.1 1160338..1160808(+) (pilA/pilA1) [Thermus thermophilus strain N-1]
ATGACTCGGCGGGGCCTTACCCTTTTGGAGCTCCTGCTGGTCTTGGGCATCCTGGGGGTCTTCCTAGGGCTGGCCCTTCC
ACTTCTTTCCCCCAACCGCCTCGCCCTGGACCAGGCCGCCCGCTCCCTCGCCACCCAGGTGACCCGGGCAAGGCTCGAGG
CCATCCGCCGGAACGCCTTCGTGGGCCTTCAGGTGTTCACCGAAGGAGCGGGGGGTTACCTGCTCTTCGTGGACCAAAAC
GCCAACCGCCGCTACGACCCCGGGGAGGAGTTCGGCGCGACCCGCTTCGGCCAAGGGAACTGGGCCCGAGTGCGCCTGGA
CCCGGAGAAGAGCGCCCTCGGCAACATGCCCCTCCTCTTTGACCCCCGGGGCATCCCGGCCAAGCCCATCACCGCCACGC
TCGTCCTCACCTCAGGGGGCGCCACCCGCAAGGTGGTCATCTCCCAGCAGGGCCGGGCCCGCCTGGAGTGA

Domains

Predicted by InterproScan.

Type II transport protein GspH (GspH)

(39-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5SIZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA/pilA1 Thermus thermophilus HB27

98.718

100

0.987