Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   HK88_RS08965 Genome accession   NC_021823
Coordinates   1771690..1773495 (-) Length   601 a.a.
NCBI ID   WP_014602170.1    Uniprot ID   A0A3T2AFB4
Organism   Listeria monocytogenes     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1766690..1778495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HK88_RS08945 (M642_09045) isdE 1767613..1768485 (-) 873 WP_003722308.1 heme ABC transporter substrate-binding protein IsdE -
  HK88_RS08950 (M642_09050) hbp2 1768572..1770281 (-) 1710 WP_014602168.1 hemin/hemoglobin-binding protein Hbp2 -
  HK88_RS08955 (M642_09055) isdC 1770296..1770919 (-) 624 WP_014602169.1 heme uptake protein IsdC -
  HK88_RS08960 (M642_09060) - 1771130..1771390 (-) 261 WP_003722311.1 DUF3116 family protein -
  HK88_RS08965 (M642_09065) pepF 1771690..1773495 (-) 1806 WP_014602170.1 oligoendopeptidase F Regulator
  HK88_RS08970 (M642_09070) - 1773568..1774683 (-) 1116 WP_009912419.1 competence protein CoiA -
  HK88_RS08975 (M642_09075) mecA 1774809..1775462 (-) 654 WP_003722314.1 adaptor protein MecA -
  HK88_RS08980 (M642_09080) spxA 1775694..1776089 (-) 396 WP_003720569.1 transcriptional regulator SpxA -
  HK88_RS08985 (M642_09085) - 1776407..1777375 (-) 969 WP_003722315.1 ABC transporter ATP-binding protein -
  HK88_RS08990 (M642_09090) - 1777372..1778448 (-) 1077 WP_003722316.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 68630.68 Da        Isoelectric Point: 4.5971

>NTDB_id=60101 HK88_RS08965 WP_014602170.1 1771690..1773495(-) (pepF) [Listeria monocytogenes]
MSKTNALPLREEVPENLTWDLTTIYPNDETWEKAFTDLQKITEESDQFKGRLSESSQTLYEALQFRDKAYDLISNLYVYA
HLKMDQDTANAKYQGLHSRAGSLVTKLMSALSYYDPEILAMDENVLKQFLDENKDLQLYDHLLEELNLSRPYILSEKEEA
LLANAGEVLGSSSNTFNTLNNADMKFPTIKDENGEDIEITHGRFGKLLESNDPRVRRDAFHGVYSVYEGLKNTLASTLNG
QVKKSNFYASTRGYTSAREAALSGNHIPETVYDSLLKSVNANASLLHRYVKLRKELLGLEELHMYDLYTPLSDNVNLEFT
YEEAKELVLEALKPLGDEYQAILKEAFDSRWIDVMENKGKRSGAYSSGSYSTNPYILLNWQDNINNVYTLAHELGHSVHS
YYTRKNQPFVYGDYSIFLAEVASTTNENLLTDYLLKKYDDPKVRAYLLNHYLDGFKGTVFRQTQFAEFEHAIHQADQQGV
ALTADFLTETYFDINKKYYGEAMVYDAEIGYEWSRIPHFYMNYYVFQYATGFSAASALSAKILTEGQDAVTAYIDFLKAG
SSDYPIDVLKKAGVDMATPNPVDDALKVFEQRLDELEELVK

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=60101 HK88_RS08965 WP_014602170.1 1771690..1773495(-) (pepF) [Listeria monocytogenes]
TTGAGTAAAACAAATGCATTACCTTTAAGAGAAGAAGTACCAGAAAATCTAACTTGGGATTTGACTACGATTTATCCGAA
TGATGAAACATGGGAAAAAGCATTTACGGATTTGCAAAAAATCACAGAGGAAAGCGACCAATTTAAAGGTCGTTTATCGG
AAAGTAGCCAAACACTTTATGAAGCACTTCAATTTCGAGATAAAGCATATGATTTGATTAGTAACTTATATGTATATGCT
CATTTGAAAATGGACCAAGATACAGCTAATGCGAAATATCAAGGTTTACATAGTCGTGCAGGAAGCCTAGTTACAAAGCT
AATGTCTGCACTCTCTTACTATGACCCAGAAATTTTAGCTATGGATGAAAATGTTCTAAAACAATTTTTAGATGAGAATA
AAGATTTACAATTATATGATCATTTGTTGGAAGAGTTAAATTTAAGTCGACCTTATATTTTGAGTGAGAAGGAAGAGGCT
TTACTAGCTAATGCAGGTGAAGTGCTTGGAAGTTCTTCCAATACTTTTAATACCTTGAATAATGCTGATATGAAGTTTCC
AACTATTAAAGATGAAAATGGGGAAGATATCGAAATTACTCATGGCCGTTTTGGGAAATTGTTAGAAAGTAATGATCCAC
GAGTGCGTCGTGATGCATTTCATGGTGTGTATTCAGTTTATGAAGGATTAAAAAACACATTAGCATCTACTTTAAATGGA
CAAGTGAAAAAATCTAATTTTTATGCTTCTACGCGAGGGTATACATCGGCTCGTGAAGCGGCTCTCTCTGGTAATCATAT
TCCTGAAACAGTATATGACTCATTGTTGAAATCAGTGAATGCTAATGCAAGTTTGCTTCATCGTTATGTGAAGTTACGTA
AGGAATTACTTGGCTTAGAAGAATTGCATATGTATGACCTTTATACGCCACTTTCTGATAATGTTAATTTGGAGTTCACT
TATGAGGAAGCAAAAGAACTCGTGCTTGAGGCGCTGAAACCACTTGGTGATGAATATCAAGCGATTTTAAAAGAGGCATT
TGATAGTCGTTGGATTGATGTGATGGAAAATAAAGGGAAACGTAGTGGAGCCTATTCTTCTGGTTCATATAGTACGAATC
CTTATATTTTACTCAATTGGCAAGATAATATTAATAATGTTTACACGCTTGCACATGAATTAGGACATAGTGTGCATAGT
TATTATACAAGAAAAAATCAACCATTTGTTTATGGTGATTATTCGATTTTCTTAGCGGAGGTTGCTTCGACTACGAATGA
AAATTTACTAACTGATTATCTGCTTAAGAAATATGATGATCCAAAAGTTCGTGCATACTTGTTGAATCACTATTTGGATG
GATTCAAGGGTACTGTATTCCGTCAAACGCAATTTGCTGAATTTGAACATGCCATTCATCAAGCGGATCAACAAGGAGTG
GCTTTGACTGCGGATTTCTTGACGGAAACATATTTTGATATTAACAAGAAATATTACGGAGAAGCGATGGTTTATGATGC
TGAAATTGGTTATGAATGGTCTCGGATTCCGCATTTTTATATGAATTATTATGTGTTCCAATATGCGACTGGTTTTTCAG
CAGCATCTGCATTAAGTGCGAAAATTTTAACAGAAGGTCAAGACGCTGTAACAGCCTATATTGATTTCTTGAAAGCAGGA
AGTTCGGATTATCCTATCGATGTGTTGAAAAAAGCAGGTGTCGATATGGCGACCCCTAATCCCGTAGATGATGCATTAAA
GGTATTTGAACAAAGATTGGATGAATTGGAAGAGCTGGTTAAATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(117-186)

Peptidase family M3 (Peptidase_M3)

(207-586)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3T2AFB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.351

98.502

0.506

Multiple sequence alignment