Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   K6969_RS09075 Genome accession   NZ_CP082205
Coordinates   1891207..1893435 (+) Length   742 a.a.
NCBI ID   WP_029174039.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1886207..1898435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS09045 (K6969_08935) - 1886488..1886973 (-) 486 WP_171942559.1 hypothetical protein -
  K6969_RS09050 (K6969_08940) - 1887216..1887788 (-) 573 WP_171942558.1 hypothetical protein -
  K6969_RS12395 (K6969_08945) - 1887748..1887888 (-) 141 WP_079267632.1 YSIRK-type signal peptide-containing protein -
  K6969_RS09055 (K6969_08950) - 1888129..1888977 (-) 849 WP_029174040.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  K6969_RS09060 (K6969_08955) - 1889211..1889945 (-) 735 WP_002943067.1 amino acid ABC transporter ATP-binding protein -
  K6969_RS09065 (K6969_08960) - 1889938..1890627 (-) 690 WP_002938702.1 amino acid ABC transporter permease -
  K6969_RS09070 (K6969_08965) - 1890753..1890983 (-) 231 WP_002938704.1 DUF1797 family protein -
  K6969_RS09075 (K6969_08970) clpE 1891207..1893435 (+) 2229 WP_029174039.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  K6969_RS09080 (K6969_08975) - 1893621..1894082 (+) 462 WP_029174038.1 NUDIX hydrolase -
  K6969_RS09085 (K6969_08980) - 1894137..1894445 (+) 309 WP_002938710.1 DUF1827 family protein -
  K6969_RS09090 (K6969_08985) ileS 1894616..1897405 (-) 2790 WP_171942557.1 isoleucine--tRNA ligase -
  K6969_RS09095 (K6969_08990) - 1897416..1897859 (-) 444 WP_171942556.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82593.94 Da        Isoelectric Point: 5.3481

>NTDB_id=600057 K6969_RS09075 WP_029174039.1 1891207..1893435(+) (clpE) [Streptococcus suis strain AKJ18]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGHEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAIEGRTQSVLGQLNNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVELGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=600057 K6969_RS09075 WP_029174039.1 1891207..1893435(+) (clpE) [Streptococcus suis strain AKJ18]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGACTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTAAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCATGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATCATTGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACTATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAAGAAGATATTCCACTCATTACTGAAAAAGAAATTGAAGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCGGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCCATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGTACTGT
CAGCTTCAAAGATACCATCATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATAGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAACAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGAGCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(153-272)

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

AAA lid domain (AAA_lid_9)

(291-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.095

100

0.834
  clpE Streptococcus pneumoniae D39

82.095

100

0.834
  clpE Streptococcus pneumoniae R6

82.095

100

0.834
  clpE Streptococcus pneumoniae TIGR4

82.095

100

0.834
  clpE Streptococcus mutans UA159

82.109

100

0.829
  clpC Lactococcus lactis subsp. cremoris KW2

77.379

97.709

0.756
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

87.601

0.46
  clpC Streptococcus thermophilus LMD-9

47.93

84.636

0.406
  clpC Streptococcus mutans UA159

48.237

84.097

0.406
  clpC Streptococcus thermophilus LMG 18311

47.611

84.636

0.403
  clpC Streptococcus pneumoniae Rx1

47.68

84.232

0.402
  clpC Streptococcus pneumoniae D39

47.68

84.232

0.402
  clpC Streptococcus pneumoniae TIGR4

47.68

84.232

0.402
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.656

84.636

0.395