Detailed information NTG0600038

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: K6969_RS02970
• Genome accession: NZ_CP082205
• Coordinates: 584582..585631 (+)
• Length: 349 a.a.
• NCBI ID: WP_044674235.1
• Uniprot ID: A0A0Z8IIM2
• Organism: Streptococcus suis strain AKJ18
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 579582..590631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6969_RS02935 (K6969_02875)	-	580098..581192 (+)	1095	WP_171942832.1	sensor histidine kinase	-
K6969_RS02940 (K6969_02880)	-	581189..581791 (+)	603	WP_171942831.1	response regulator transcription factor	-
K6969_RS02945 (K6969_02885)	-	581896..582114 (+)	219	WP_024380322.1	YqgQ family protein	-
K6969_RS02950 (K6969_02890)	-	582114..582500 (+)	387	WP_029173425.1	rhodanese-like domain-containing protein	-
K6969_RS02955 (K6969_02895)	-	582557..583279 (+)	723	WP_024385934.1	hypothetical protein	-
K6969_RS02960 (K6969_02900)	rsmD	583578..584117 (+)	540	WP_171942830.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
K6969_RS02965 (K6969_02905)	coaD	584107..584595 (+)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
K6969_RS02970 (K6969_02910)	sepM	584582..585631 (+)	1050	WP_044674235.1	SepM family pheromone-processing serine protease	Regulator
K6969_RS02975 (K6969_02915)	-	585819..586460 (+)	642	WP_014638483.1	YutD family protein	-
K6969_RS02980 (K6969_02920)	rlmN	586469..587581 (+)	1113	WP_002942845.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
K6969_RS02985 (K6969_02925)	-	587578..588102 (+)	525	WP_029173428.1	VanZ family protein	-
K6969_RS02990 (K6969_02930)	trpB	588794..589969 (+)	1176	WP_171942829.1	tryptophan synthase subunit beta	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.72 Da
• Isoelectric Point: 4.4261

>NTDB_id=600038 K6969_RS02970 WP_044674235.1 584582..585631(+) (sepM) [Streptococcus suis strain AKJ18]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTIRSSEEMTGGADNEEYFRIAQFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALADDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLELGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKEDPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=600038 K6969_RS02970 WP_044674235.1 584582..585631(+) (sepM) [Streptococcus suis strain AKJ18]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCCACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAATTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAAGAGTATTTTCGTATAGCACAGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTACTTGCCTTGGCGGATGATTCGACCTTTAAAAAAGTTCTTAATATTGCTGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATAAAATATGTGAGTGGCTTGGAACTTGGAAGTGATGTGACAGTTGGTTATATTAG
CGCCGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATTACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATCTTTTTTG
TACCAAATAATCCAGTTGATGTGGAAGTTTTGAAGGAAGATCCAAAGGCTAAAACCAACTATGAGGAAGCTAAAGAAGCT
GCGGAGAAAGCAGGGTTGGATATTGAGGTAGTTCCTGTAAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-311)

• PDZ domain (PDZ_2) (132-195)

3D structure

• AlphaFold DB: A0A0Z8IIM2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	61.095	99.427	0.607