Detailed information NTG0600004

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: K6974_RS09845
• Genome accession: NZ_CP082204
• Coordinates: 1968937..1969986 (-)
• Length: 349 a.a.
• NCBI ID: WP_043026533.1
• Uniprot ID: -
• Organism: Streptococcus suis strain FJSM5
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1963937..1974986

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6974_RS09825 (K6974_09720)	trpB	1964763..1965938 (-)	1176	WP_222337154.1	tryptophan synthase subunit beta	-
K6974_RS09830 (K6974_09725)	-	1966469..1966990 (-)	522	WP_222337153.1	VanZ family protein	-
K6974_RS09835 (K6974_09730)	rlmN	1966987..1968099 (-)	1113	WP_024375852.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
K6974_RS09840 (K6974_09735)	-	1968108..1968749 (-)	642	WP_043026531.1	YutD-like domain-containing protein	-
K6974_RS09845 (K6974_09740)	sepM	1968937..1969986 (-)	1050	WP_043026533.1	SepM family pheromone-processing serine protease	Regulator
K6974_RS09850 (K6974_09745)	coaD	1969973..1970461 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
K6974_RS09855 (K6974_09750)	rsmD	1970451..1970990 (-)	540	WP_043026535.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
K6974_RS09860 (K6974_09755)	-	1971291..1972013 (-)	723	WP_043026537.1	serine protease	-
K6974_RS09865 (K6974_09760)	-	1972070..1972456 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
K6974_RS09870 (K6974_09765)	-	1972456..1972674 (-)	219	WP_024375849.1	YqgQ family protein	-
K6974_RS09875 (K6974_09770)	-	1972778..1973380 (-)	603	WP_099806780.1	response regulator transcription factor	-
K6974_RS09880 (K6974_09775)	-	1973377..1974471 (-)	1095	WP_161944334.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37732.74 Da
• Isoelectric Point: 4.4632

>NTDB_id=600004 K6974_RS09845 WP_043026533.1 1968937..1969986(-) (sepM) [Streptococcus suis strain FJSM5]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTIRSSEEMTGGADNEEYFRIAQFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALADDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLELGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKENPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=600004 K6974_RS09845 WP_043026533.1 1968937..1969986(-) (sepM) [Streptococcus suis strain FJSM5]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAATTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAAGAGTATTTCCGTATAGCACAGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTACTTGCCTTGGCGGATGATTCGACCTTTAAAAAAGTTCTTAATATTGCTGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAACTTGGAAGTGATGTGACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATCTTTTTCG
TACCAAATAATCCAGTTGATGTGGAAGTTTTGAAGGAAAATCCAAAGGCTAAAACCAACTATGAGGAAGCTAAAGAAGCT
GCGGAGAAAGCAGGATTGGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-314)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	61.383	99.427	0.61