Detailed information NTG0599902

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: K6976_RS09880
• Genome accession: NZ_CP082202
• Coordinates: 2061126..2063576 (-)
• Length: 816 a.a.
• NCBI ID: WP_222759413.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SS389
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2056126..2068576

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6976_RS09860 (K6976_09860)	hslO	2057853..2058719 (+)	867	WP_024407276.1	Hsp33 family molecular chaperone HslO	-
K6976_RS09865 (K6976_09865)	dusB	2058712..2059716 (+)	1005	WP_105152945.1	tRNA dihydrouridine synthase DusB	-
K6976_RS09870 (K6976_09870)	-	2059820..2060308 (-)	489	WP_222759411.1	adenylyltransferase/cytidyltransferase family protein	-
K6976_RS09875 (K6976_09875)	-	2060620..2061117 (-)	498	WP_202822152.1	GNAT family N-acetyltransferase	-
K6976_RS09880 (K6976_09880)	clpC	2061126..2063576 (-)	2451	WP_222759413.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
K6976_RS09885 (K6976_09885)	-	2063580..2064038 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
K6976_RS09890 (K6976_09890)	-	2064307..2064645 (+)	339	WP_105211701.1	thioredoxin domain-containing protein	-
K6976_RS09895 (K6976_09895)	-	2064645..2065271 (+)	627	WP_222759414.1	GNAT family acetyltransferase	-
K6976_RS09900 (K6976_09900)	-	2065537..2066739 (+)	1203	WP_315985283.1	IS110 family transposase	-
K6976_RS09905 (K6976_09905)	tsf	2067388..2068428 (-)	1041	WP_222759418.1	translation elongation factor Ts	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90534.07 Da
• Isoelectric Point: 6.0469

>NTDB_id=599902 K6976_RS09880 WP_222759413.1 2061126..2063576(-) (clpC) [Streptococcus suis strain SS389]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSIASQILDKVGFYFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALDLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGDTAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAVTAEKGINLKLQPSALKLLAKQGYDLEMGARPLRRLLQTKLEDPLAEMLLRGELSAGST
LKVGVKGEELKFDVVK

Nucleotide

• Length: 2451 bp

>NTDB_id=599902 K6976_RS09880 WP_222759413.1 2061126..2063576(-) (clpC) [Streptococcus suis strain SS389]
ATGAAAATTTCAACTGGTTTACAACGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCCGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
GCATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAATAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTATTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGACTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACTAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTGGTTGGTGATGCAGGTGTC
GGAAAAACTGCGCTTGCTTTGGATCTTGCTCAACGTGTTGCTGCAGGTGATGTTCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGATATCGAGGAAGATGGTCAGGTCATCCTCTTCATCGATGAGTTGCATACCATTATGGGTTCAGGGTCAGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACAACTCAGAC
AGAGTATCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAGAAATACCACAGGGTCCGTATTGGAGATACTGCTGTT
GAAACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCTGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACGGGACTGACGAGTATTGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATTCCTGTAGCCAAGCTCAGTCAGTCAGATACCAAGAA
ATATCTGAATTTGGAAGCAGAACTGCATAAACGTGTCATCGGTCAAGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAG
ACTGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGACGAATCTGCTCTTATCCGTTTTGATATGTCTGAATACAT
GGAGAAATTCGCAGCCAGTCGTCTCAATGGAGCGCCTCCGGGCTACGTGGGCTATGAGGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTTTTG
CAGGTCTTGGATGATGGTGTTCTGACAGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTAACCTTAAACTGCAACCGTCAGCCCTCAAGTTATTGGCTAAACAAGGTTACGACCTAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTACAGACCAAATTGGAAGACCCATTGGCAGAAATGTTGCTCCGTGGTGAGTTGTCTGCTGGTTCGACC
TTGAAGGTTGGGGTAAAGGGCGAAGAGCTCAAGTTTGATGTGGTCAAATAG

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (372-457)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-130)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.779	99.877	0.717
clpC	Streptococcus pneumoniae D39	71.779	99.877	0.717
clpC	Streptococcus pneumoniae TIGR4	71.779	99.877	0.717
clpC	Streptococcus mutans UA159	66.462	99.755	0.663
clpC	Streptococcus thermophilus LMG 18311	64.26	100	0.654
clpC	Streptococcus thermophilus LMD-9	64.14	100	0.653
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.341	100	0.505
clpC	Bacillus subtilis subsp. subtilis str. 168	43.473	100	0.445