Detailed information NTG0599842

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: K6967_RS07745
• Genome accession: NZ_CP082201
• Coordinates: 1562919..1563968 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain Transconjugant cAKJ18
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1557919..1568968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6967_RS07725 (K6967_07725)	nadE	1558325..1559149 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
K6967_RS07730 (K6967_07730)	-	1560445..1560972 (-)	528	WP_012027591.1	VanZ family protein	-
K6967_RS07735 (K6967_07735)	rlmN	1560969..1562081 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
K6967_RS07740 (K6967_07740)	-	1562090..1562731 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
K6967_RS07745 (K6967_07745)	sepM	1562919..1563968 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
K6967_RS07750 (K6967_07750)	coaD	1563955..1564443 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
K6967_RS07755 (K6967_07755)	rsmD	1564433..1564972 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
K6967_RS07760 (K6967_07760)	-	1565280..1566002 (-)	723	WP_012027598.1	lipoprotein	-
K6967_RS07765 (K6967_07765)	-	1566059..1566445 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
K6967_RS07770 (K6967_07770)	-	1566445..1566663 (-)	219	WP_004194736.1	YqgQ family protein	-
K6967_RS07775 (K6967_07775)	-	1566971..1567573 (-)	603	WP_012027601.1	response regulator transcription factor	-
K6967_RS07780 (K6967_07780)	-	1567570..1568664 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=599842 K6967_RS07745 WP_012775295.1 1562919..1563968(-) (sepM) [Streptococcus suis strain Transconjugant cAKJ18]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=599842 K6967_RS07745 WP_012775295.1 1562919..1563968(-) (sepM) [Streptococcus suis strain Transconjugant cAKJ18]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605