Detailed information NTG0599790

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: K6971_RS07745
• Genome accession: NZ_CP082200
• Coordinates: 1562367..1563416 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain Transconjugant cDY107
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1557367..1568416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6971_RS07725 (K6971_07725)	nadE	1557773..1558597 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
K6971_RS07730 (K6971_07730)	-	1559893..1560420 (-)	528	WP_012027591.1	VanZ family protein	-
K6971_RS07735 (K6971_07735)	rlmN	1560417..1561529 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
K6971_RS07740 (K6971_07740)	-	1561538..1562179 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
K6971_RS07745 (K6971_07745)	sepM	1562367..1563416 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
K6971_RS07750 (K6971_07750)	coaD	1563403..1563891 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
K6971_RS07755 (K6971_07755)	rsmD	1563881..1564420 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
K6971_RS07760 (K6971_07760)	-	1564728..1565450 (-)	723	WP_012027598.1	lipoprotein	-
K6971_RS07765 (K6971_07765)	-	1565507..1565893 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
K6971_RS07770 (K6971_07770)	-	1565893..1566111 (-)	219	WP_004194736.1	YqgQ family protein	-
K6971_RS07775 (K6971_07775)	-	1566419..1567021 (-)	603	WP_012027601.1	response regulator transcription factor	-
K6971_RS07780 (K6971_07780)	-	1567018..1568112 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=599790 K6971_RS07745 WP_012775295.1 1562367..1563416(-) (sepM) [Streptococcus suis strain Transconjugant cDY107]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=599790 K6971_RS07745 WP_012775295.1 1562367..1563416(-) (sepM) [Streptococcus suis strain Transconjugant cDY107]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605