Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | K6975_RS09000 | Genome accession | NZ_CP082197 |
| Coordinates | 1843667..1846120 (-) | Length | 817 a.a. |
| NCBI ID | WP_012027858.1 | Uniprot ID | A0A2K1SY42 |
| Organism | Streptococcus suis strain Transconjugant cSS389 | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1839769..1882996 | 1843667..1846120 | within | 0 |
Gene organization within MGE regions
Location: 1839769..1882996
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6975_RS08980 (K6975_08980) | dusB | 1839769..1840773 (+) | 1005 | WP_012775355.1 | tRNA dihydrouridine synthase DusB | - |
| K6975_RS08985 (K6975_08985) | - | 1840919..1841692 (-) | 774 | WP_012027854.1 | NUDIX domain-containing protein | - |
| K6975_RS08990 (K6975_08990) | pnuC | 1841685..1842506 (-) | 822 | WP_012027855.1 | nicotinamide riboside transporter PnuC | - |
| K6975_RS08995 (K6975_08995) | - | 1842516..1843553 (-) | 1038 | WP_012028524.1 | AAA family ATPase | - |
| K6975_RS09000 (K6975_09000) | clpC | 1843667..1846120 (-) | 2454 | WP_012027858.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| K6975_RS09005 (K6975_09005) | - | 1846126..1846584 (-) | 459 | WP_012027859.1 | CtsR family transcriptional regulator | - |
| K6975_RS09010 (K6975_09010) | - | 1846734..1847072 (+) | 339 | WP_012027860.1 | thioredoxin domain-containing protein | - |
| K6975_RS09015 (K6975_09015) | - | 1847072..1847773 (+) | 702 | WP_012027861.1 | hypothetical protein | - |
| K6975_RS09020 (K6975_09020) | tsf | 1848036..1849076 (-) | 1041 | WP_012027862.1 | translation elongation factor Ts | - |
| K6975_RS09025 (K6975_09025) | rpsB | 1849232..1850008 (-) | 777 | WP_012775356.1 | 30S ribosomal protein S2 | - |
| K6975_RS09030 (K6975_09030) | - | 1850355..1850867 (-) | 513 | WP_012775452.1 | adenylate kinase | - |
| K6975_RS09040 (K6975_09040) | - | 1851521..1856599 (-) | 5079 | WP_012775357.1 | S8 family serine peptidase | - |
| K6975_RS09045 (K6975_09045) | nusG | 1856743..1857282 (-) | 540 | WP_002940254.1 | transcription termination/antitermination protein NusG | - |
| K6975_RS09050 (K6975_09050) | secE | 1857392..1857568 (-) | 177 | WP_002940255.1 | preprotein translocase subunit SecE | - |
| K6975_RS09055 (K6975_09055) | rpmG | 1857578..1857730 (-) | 153 | WP_002940258.1 | 50S ribosomal protein L33 | - |
| K6975_RS09060 (K6975_09060) | pbp2a | 1857764..1859977 (-) | 2214 | WP_012027868.1 | penicillin-binding protein PBP2A | - |
| K6975_RS09065 (K6975_09065) | - | 1860130..1861098 (+) | 969 | WP_012027869.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| K6975_RS09070 (K6975_09070) | - | 1861100..1861966 (+) | 867 | WP_012027870.1 | RluA family pseudouridine synthase | - |
| K6975_RS09075 (K6975_09075) | purR | 1861993..1862805 (-) | 813 | WP_002938438.1 | pur operon repressor | - |
| K6975_RS09080 (K6975_09080) | - | 1862907..1863773 (-) | 867 | WP_012027872.1 | aminoglycoside phosphotransferase family protein | - |
| K6975_RS09085 (K6975_09085) | - | 1863773..1864714 (-) | 942 | WP_012775359.1 | 3'-5' exoribonuclease YhaM family protein | - |
| K6975_RS09090 (K6975_09090) | - | 1864704..1865942 (-) | 1239 | WP_012027874.1 | DNA recombination protein RmuC | - |
| K6975_RS09095 (K6975_09095) | - | 1865943..1866575 (-) | 633 | WP_012027875.1 | thiamine diphosphokinase | - |
| K6975_RS09100 (K6975_09100) | rpe | 1866568..1867227 (-) | 660 | WP_012027876.1 | ribulose-phosphate 3-epimerase | - |
| K6975_RS09105 (K6975_09105) | rsgA | 1867242..1868117 (-) | 876 | WP_012027877.1 | ribosome small subunit-dependent GTPase A | - |
| K6975_RS09115 (K6975_09115) | - | 1869014..1870591 (-) | 1578 | WP_012027878.1 | ABC transporter ATP-binding protein | - |
| K6975_RS09120 (K6975_09120) | - | 1870588..1871829 (-) | 1242 | WP_014636518.1 | radical SAM protein | - |
| K6975_RS09125 (K6975_09125) | - | 1872198..1873061 (-) | 864 | WP_012027880.1 | helix-turn-helix domain-containing protein | - |
| K6975_RS09130 (K6975_09130) | - | 1873551..1875995 (-) | 2445 | WP_012027881.1 | LTA synthase family protein | - |
| K6975_RS09135 (K6975_09135) | - | 1876008..1877738 (-) | 1731 | WP_012775361.1 | membrane protein | - |
| K6975_RS09140 (K6975_09140) | rsmA | 1878103..1878975 (-) | 873 | WP_012775362.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
| K6975_RS09145 (K6975_09145) | - | 1878995..1879525 (-) | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
| K6975_RS09150 (K6975_09150) | - | 1879539..1879796 (-) | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | - |
| K6975_RS09155 (K6975_09155) | - | 1879798..1880058 (-) | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| K6975_RS09160 (K6975_09160) | - | 1880134..1880589 (-) | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
| K6975_RS09165 (K6975_09165) | - | 1880596..1880925 (-) | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| K6975_RS09170 (K6975_09170) | - | 1880915..1881202 (-) | 288 | WP_012028535.1 | hypothetical protein | - |
| K6975_RS09175 (K6975_09175) | - | 1881300..1881668 (-) | 369 | WP_012775453.1 | hypothetical protein | - |
| K6975_RS09180 (K6975_09180) | rnmV | 1881661..1882230 (-) | 570 | WP_012775366.1 | ribonuclease M5 | - |
| K6975_RS09185 (K6975_09185) | - | 1882214..1882996 (-) | 783 | WP_012028536.1 | TatD family hydrolase | - |
Sequence
Protein
Download Length: 817 a.a. Molecular weight: 90132.53 Da Isoelectric Point: 6.3138
>NTDB_id=599641 K6975_RS09000 WP_012027858.1 1843667..1846120(-) (clpC) [Streptococcus suis strain Transconjugant cSS389]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
Nucleotide
Download Length: 2454 bp
>NTDB_id=599641 K6975_RS09000 WP_012027858.1 1843667..1846120(-) (clpC) [Streptococcus suis strain Transconjugant cSS389]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae TIGR4 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae Rx1 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae D39 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus mutans UA159 |
66.173 |
99.143 |
0.656 |
| clpC | Streptococcus thermophilus LMG 18311 |
64.828 |
99.878 |
0.647 |
| clpC | Streptococcus thermophilus LMD-9 |
64.706 |
99.878 |
0.646 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.086 |
100 |
0.492 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.403 |
99.51 |
0.442 |