Detailed information NTG0599634

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: K6975_RS07665
• Genome accession: NZ_CP082197
• Coordinates: 1560122..1561171 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain Transconjugant cSS389
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1555122..1566171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6975_RS07645 (K6975_07645)	nadE	1555528..1556352 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
K6975_RS07650 (K6975_07650)	-	1557648..1558175 (-)	528	WP_012027591.1	VanZ family protein	-
K6975_RS07655 (K6975_07655)	rlmN	1558172..1559284 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
K6975_RS07660 (K6975_07660)	-	1559293..1559934 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
K6975_RS07665 (K6975_07665)	sepM	1560122..1561171 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
K6975_RS07670 (K6975_07670)	coaD	1561158..1561646 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
K6975_RS07675 (K6975_07675)	rsmD	1561636..1562175 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
K6975_RS07680 (K6975_07680)	-	1562483..1563205 (-)	723	WP_012027598.1	lipoprotein	-
K6975_RS07685 (K6975_07685)	-	1563262..1563648 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
K6975_RS07690 (K6975_07690)	-	1563648..1563866 (-)	219	WP_004194736.1	YqgQ family protein	-
K6975_RS07695 (K6975_07695)	-	1564174..1564776 (-)	603	WP_012027601.1	response regulator transcription factor	-
K6975_RS07700 (K6975_07700)	-	1564773..1565867 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=599634 K6975_RS07665 WP_012775295.1 1560122..1561171(-) (sepM) [Streptococcus suis strain Transconjugant cSS389]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=599634 K6975_RS07665 WP_012775295.1 1560122..1561171(-) (sepM) [Streptococcus suis strain Transconjugant cSS389]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605