Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   NB631_RS12325 Genome accession   NZ_CP098257
Coordinates   2525145..2526419 (-) Length   424 a.a.
NCBI ID   WP_001279341.1    Uniprot ID   -
Organism   Staphylococcus aureus strain M4     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2520145..2531419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NB631_RS12315 (NB631_12325) - 2522503..2523408 (-) 906 WP_000184374.1 transglycosylase domain-containing protein -
  NB631_RS12320 (NB631_12330) tyrS 2523789..2525051 (+) 1263 WP_000186043.1 tyrosine--tRNA ligase -
  NB631_RS12325 (NB631_12335) htrA 2525145..2526419 (-) 1275 WP_001279341.1 trypsin-like peptidase domain-containing protein Regulator
  NB631_RS12330 (NB631_12340) - 2526591..2527208 (+) 618 WP_000287585.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  NB631_RS12335 (NB631_12345) nagE 2527336..2528802 (+) 1467 WP_000276356.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  NB631_RS12340 (NB631_12350) - 2528908..2530038 (+) 1131 WP_000721720.1 HAD family hydrolase -
  NB631_RS12345 (NB631_12355) - 2529999..2530094 (-) 96 WP_031761395.1 hypothetical protein -

Sequence

Protein


Download         Length: 424 a.a.        Molecular weight: 45733.87 Da        Isoelectric Point: 9.8964

>NTDB_id=599110 NB631_RS12325 WP_001279341.1 2525145..2526419(-) (htrA) [Staphylococcus aureus strain M4]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDSEDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide


Download         Length: 1275 bp        

>NTDB_id=599110 NB631_RS12325 WP_001279341.1 2525145..2526419(-) (htrA) [Staphylococcus aureus strain M4]
ATGTCAGATTTTAATCATACAGATCATTCAACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATCATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTCCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAATATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCCGGTGTAGGCTCAGGTGTCATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTCGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGTGAACGTACTATTGACGCAGAGACAACTGGTGGTAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATTGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATAGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATACCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGCGAAGACGGTATTTATGTCGCAAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAGCCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACTAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(307-397)

Trypsin-like peptidase domain (Trypsin_2)

(125-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

38.806

94.811

0.368