Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   KFZ57_RS03585 Genome accession   NZ_CP098229
Coordinates   742805..743464 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain XJ55     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 737805..748464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFZ57_RS03560 (KFZ57_03560) - 738547..739494 (+) 948 WP_001377068.1 iron-siderophore ABC transporter substrate-binding protein -
  KFZ57_RS03565 (KFZ57_03565) - 739491..740378 (+) 888 WP_000614956.1 MurR/RpiR family transcriptional regulator -
  KFZ57_RS03570 (KFZ57_03570) ygiN 740423..740737 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  KFZ57_RS03575 (KFZ57_03575) mdaB 740768..741349 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  KFZ57_RS03580 (KFZ57_03580) qseC 741459..742808 (-) 1350 WP_001544946.1 quorum sensing histidine kinase QseC -
  KFZ57_RS03585 (KFZ57_03585) ciaR 742805..743464 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  KFZ57_RS03590 (KFZ57_03590) ygiW 743616..744008 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  KFZ57_RS03595 (KFZ57_03595) ygiV 744061..744543 (+) 483 WP_000183492.1 AraC family transcriptional regulator -
  KFZ57_RS03600 (KFZ57_03600) parC 745089..747347 (+) 2259 WP_001281881.1 DNA topoisomerase IV subunit A -
  KFZ57_RS03605 (KFZ57_03605) plsC 747581..748318 (+) 738 WP_000965712.1 1-acylglycerol-3-phosphate O-acyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=598640 KFZ57_RS03585 WP_001221493.1 742805..743464(-) (ciaR) [Escherichia coli strain XJ55]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=598640 KFZ57_RS03585 WP_001221493.1 742805..743464(-) (ciaR) [Escherichia coli strain XJ55]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGTGCGCCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGTTAGCGGAACGTGTCGAGGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAACTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGTGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTACCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365