Detailed information NTG0596911

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: K4120_RS16770
• Genome accession: NZ_CP081488
• Coordinates: 3426849..3428012 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain LZN01
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3421849..3433012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K4120_RS16740 (K4120_16740)	-	3422113..3422532 (-)	420	WP_007407479.1	TIGR03826 family flagellar region protein	-
K4120_RS16745 (K4120_16745)	comFC	3422606..3423295 (-)	690	WP_197061611.1	phosphoribosyltransferase family protein	Machinery gene
K4120_RS16750 (K4120_16750)	-	3423301..3423585 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
K4120_RS16755 (K4120_16755)	comFA	3423643..3425028 (-)	1386	WP_007407482.1	DEAD/DEAH box helicase	Machinery gene
K4120_RS16760 (K4120_16760)	-	3425137..3425985 (-)	849	WP_007407483.1	DegV family protein	-
K4120_RS16765 (K4120_16765)	degU	3426083..3426772 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
K4120_RS16770 (K4120_16770)	degS	3426849..3428012 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
K4120_RS16775 (K4120_16775)	-	3428235..3428882 (+)	648	WP_007407485.1	YigZ family protein	-
K4120_RS16780 (K4120_16780)	-	3428887..3430107 (+)	1221	WP_032867080.1	LCP family protein	-
K4120_RS16785 (K4120_16785)	-	3430206..3431282 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
K4120_RS16790 (K4120_16790)	-	3431415..3432611 (-)	1197	WP_032867083.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=596911 K4120_RS16770 WP_007407484.1 3426849..3428012(-) (degS) [Bacillus velezensis strain LZN01]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=596911 K4120_RS16770 WP_007407484.1 3426849..3428012(-) (degS) [Bacillus velezensis strain LZN01]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCTTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
ATCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951