Detailed information NTG0596643

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: M9H69_RS08425
• Genome accession: NZ_CP097843
• Coordinates: 1662976..1665081 (-)
• Length: 701 a.a.
• NCBI ID: WP_250315383.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain HP01
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1657976..1670081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS08395 (M9H69_08395)	-	1658209..1659240 (-)	1032	WP_250315378.1	HAMP domain-containing sensor histidine kinase	-
M9H69_RS08400 (M9H69_08400)	-	1659207..1659905 (-)	699	WP_250315379.1	response regulator transcription factor	-
M9H69_RS08405 (M9H69_08405)	-	1659918..1660640 (-)	723	WP_250315380.1	lantibiotic ABC transporter permease	-
M9H69_RS08410 (M9H69_08410)	-	1660640..1661428 (-)	789	WP_250315381.1	ABC transporter permease	-
M9H69_RS08415 (M9H69_08415)	-	1661430..1662137 (-)	708	WP_084872489.1	ATP-binding cassette domain-containing protein	-
M9H69_RS08420 (M9H69_08420)	-	1662434..1662916 (+)	483	WP_250315382.1	S-ribosylhomocysteine lyase	-
M9H69_RS08425 (M9H69_08425)	clpE	1662976..1665081 (-)	2106	WP_250315383.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
M9H69_RS08430 (M9H69_08430)	pflB	1665474..1667789 (-)	2316	WP_000260614.1	formate C-acetyltransferase	-
M9H69_RS08435 (M9H69_08435)	dinB	1668026..1669087 (+)	1062	WP_195216119.1	DNA polymerase IV	-
M9H69_RS08440 (M9H69_08440)	-	1669121..1669966 (-)	846	WP_250315384.1	undecaprenyl-diphosphate phosphatase	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77460.25 Da
• Isoelectric Point: 4.7655

>NTDB_id=596643 M9H69_RS08425 WP_250315383.1 1662976..1665081(-) (clpE) [Streptococcus oralis strain HP01]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAEVDGQMQQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSIGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNAKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLEHKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLNKEDLSKIVDLMLAEVNQTLAKKGIDLEVS
QAAKDFITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide

• Length: 2106 bp

>NTDB_id=596643 M9H69_RS08425 WP_250315383.1 1662976..1665081(-) (clpE) [Streptococcus oralis strain HP01]
ATGAACAACAACTTTAATAACTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAACCGTCGCTACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTCACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAAGTTGATGGACAAATGCAACAACAAGCTTCAGGTATGAAACAAGACGGTGTCCTTGCTAAACTAGGT
CGTAACTTGACCGCAGAAGCTCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATCCTCTCACGTCGTACGAAAAATAATCCTGTTCTGGTCGGAGATGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGCT
TAGCACAAGCTATTGTGAATGGAGATGTTCCAGCTGCCATCAAGAATAAGGAAATTATTTCTATTGATATCTCAGGTCTT
GAAGCTGGTACTCAATACCGTGGCAGCTTTGAAGAAAACGTTCAAAACCTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATCCTTGGTGCTGGTTCAATCGGTGGAGACAGTGGTTCTAAAGGTCTTGCAG
ATATTCTCAAGCCAGCTCTCTCTCGTGGTGAATTGACCGTTATTGGAGCGACAACTCAAGACGAATACCGTAACACCATC
TTGAAAAATGCAGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGGATACCTTTAAAATCCT
TCAAGGGATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCAGTGGATTATT
CTGTCCAATACATTCCTCAACGCAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCAGCTCACTTGGCAGCT
CAACATCCAGTAACAGATGTTCATGCTGTCGAACGGGAAATCGAGGCAGAAAAGGACAAGCAAGAAAAAGCAGTTGAGGC
AGAAGATTTCGAAGCAGCTCTTAATGCTAAAACACGCATTGCAGAATTAGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAGGTGACTGCGAGTGTCAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCGGTATCACAAATGGGAGCA
TCAGACATCGAACGTTTGAAAGATATGGCTCATCGTTTGGAACACAAGGTTATCGGCCAAGATAAGGCAGTAGAAGCAGT
GGCTCGTGCTATCCGTCGTAACCGTGCAGGATTTGATGAAGGCAATCGCCCAATCGGTAGCTTCCTCTTTGTAGGGCCTA
CTGGGGTTGGGAAGACCGAGCTTGCTAAGCAATTGGCGCTCGATATGTTTGGAACCAAGGATGCGATCATCCGCTTGGAT
ATGTCTGAATACAGTGACCGCACAGCCGTTTCTAAGTTAATCGGTACAACAGCAGGTTATGTGGGTTATGATGACAATAG
CAATACCTTGACAGAACGTGTTCGTCGCAATCCTTACTCTATCATTCTCTTGGACGAAATTGAAAAGGCTGATCCTCAAG
TCATTACCCTTCTCCTCCAAGTCTTGGATGACGGCCGTTTAACTGATGGTCAAGGAAATACCGTGAACTTCAAAAACACT
GTCATTATCGCAACATCAAATGCTGGATTTGGCTATGAAGCTAACTTGACGGAAGATGCAGACAAACCAGAATTGATGGA
TCGTTTGAAACCATACTTCCGTCCAGAATTCCTCAATCGCTTTAATGCAGTTATCGAGTTCTCACACTTGAATAAGGAAG
ACCTTTCTAAGATTGTGGACTTGATGTTGGCTGAAGTCAACCAAACCTTGGCTAAGAAAGGAATCGACCTTGAAGTTAGC
CAAGCAGCTAAGGACTTTATCACAGAAGAAGGCTATGACGAAGTTATGGGTGTTCGTCCTCTCCGTCGCGTGGTTGAACA
ACAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATCTAGATGCCAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTCATTCGTGAAAAAGCCTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (610-680)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA lid domain (AAA_lid_9) (259-354)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	50.466	91.869	0.464
clpC	Lactococcus lactis subsp. cremoris KW2	49.844	91.298	0.455
clpE	Streptococcus pneumoniae D39	48.819	90.585	0.442
clpE	Streptococcus pneumoniae R6	48.819	90.585	0.442
clpE	Streptococcus pneumoniae Rx1	48.819	90.585	0.442
clpE	Streptococcus pneumoniae TIGR4	48.819	90.585	0.442
clpC	Bacillus subtilis subsp. subtilis str. 168	44.992	92.582	0.417
clpC	Streptococcus pneumoniae Rx1	43.269	89.016	0.385
clpC	Streptococcus pneumoniae D39	43.269	89.016	0.385
clpC	Streptococcus pneumoniae TIGR4	43.109	89.016	0.384
clpC	Streptococcus thermophilus LMD-9	43.274	88.017	0.381
clpC	Streptococcus thermophilus LMG 18311	43.112	88.017	0.379
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.95	88.017	0.378
clpC	Streptococcus mutans UA159	42.233	88.16	0.372