Detailed information NTG0596140

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: K1X69_RS13945
• Genome accession: NZ_CP081354
• Coordinates: 2772451..2773338 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain SQL1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2767451..2778338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K1X69_RS13915 (K1X69_13910)	-	2767470..2767562 (+)	93	WP_010956583.1	hypothetical protein	-
K1X69_RS13920 (K1X69_13915)	-	2767670..2768167 (-)	498	WP_001065268.1	glutathione peroxidase	-
K1X69_RS13925 (K1X69_13920)	-	2768177..2768437 (-)	261	WP_001789910.1	hypothetical protein	-
K1X69_RS13930 (K1X69_13925)	-	2768819..2768932 (-)	114	WP_001791776.1	hypothetical protein	-
K1X69_RS13935 (K1X69_13930)	-	2769591..2771591 (-)	2001	WP_000776751.1	ABC transporter permease	-
K1X69_RS13940 (K1X69_13935)	-	2771588..2772343 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
K1X69_RS13945 (K1X69_13940)	braS	2772451..2773338 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
K1X69_RS13950 (K1X69_13945)	braR	2773349..2774014 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
K1X69_RS13955 (K1X69_13950)	-	2774040..2774240 (-)	201	WP_000604728.1	hypothetical protein	-
K1X69_RS13960 (K1X69_13955)	-	2774438..2775862 (+)	1425	WP_000953744.1	alkaline phosphatase	-
K1X69_RS14720	-	2775922..2776023 (-)	102	WP_000731972.1	SE2200 family small protein	-
K1X69_RS13970 (K1X69_13965)	-	2776145..2776600 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
K1X69_RS13975 (K1X69_13970)	-	2776845..2777606 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=596140 K1X69_RS13945 WP_000143419.1 2772451..2773338(-) (braS) [Staphylococcus aureus strain SQL1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=596140 K1X69_RS13945 WP_000143419.1 2772451..2773338(-) (braS) [Staphylococcus aureus strain SQL1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997