Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M8Y68_RS09085 Genome accession   NZ_CP097430
Coordinates   1889515..1890171 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain C288     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1884515..1895171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8Y68_RS09055 (M8Y68_09055) dcyD 1885395..1886381 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M8Y68_RS09060 (M8Y68_09060) tcyL 1886396..1887064 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  M8Y68_RS09065 (M8Y68_09065) tcyN 1887061..1887813 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M8Y68_RS09070 (M8Y68_09070) sdiA 1888043..1888765 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  M8Y68_RS09075 (M8Y68_09075) yecF 1888832..1889056 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M8Y68_RS09080 (M8Y68_09080) yecU 1889043..1889219 (-) 177 WP_001326718.1 protein YecU -
  M8Y68_RS24515 - 1889302..1889373 (-) 72 Protein_1779 transcriptional regulator -
  M8Y68_RS09085 (M8Y68_09085) letA 1889515..1890171 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M8Y68_RS09090 (M8Y68_09090) uvrC 1890168..1892000 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M8Y68_RS09095 (M8Y68_09095) pgsA 1892057..1892605 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M8Y68_RS09115 (M8Y68_09115) - 1893370..1894067 (+) 698 WP_151884388.1 IS1 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=595032 M8Y68_RS09085 WP_000611335.1 1889515..1890171(+) (letA) [Escherichia coli strain C288]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=595032 M8Y68_RS09085 WP_000611335.1 1889515..1890171(+) (letA) [Escherichia coli strain C288]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486