Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   HLV54_RS10430 Genome accession   NZ_CP080770
Coordinates   2100995..2101711 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain HL23187     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2095995..2106711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLV54_RS10400 (HLV54_002080) - 2096212..2096838 (+) 627 WP_000522383.1 nitroreductase family protein -
  HLV54_RS10405 (HLV54_002081) - 2097199..2097984 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  HLV54_RS14320 hld 2098583..2098663 (-) 81 WP_000046023.1 delta-hemolysin -
  HLV54_RS10415 (HLV54_002083) agrB 2098953..2099522 (+) 570 WP_001105712.1 accessory gene regulator AgrB -
  HLV54_RS10420 (HLV54_002084) agrD 2099519..2099659 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  HLV54_RS10425 (HLV54_002085) agrC 2099684..2100976 (+) 1293 WP_031844950.1 quorum-sensing sensor histidine kinase AgrC -
  HLV54_RS10430 (HLV54_002086) agrA 2100995..2101711 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  HLV54_RS10435 (HLV54_002087) - 2101783..2101890 (+) 108 WP_031844951.1 hypothetical protein -
  HLV54_RS10440 (HLV54_002088) - 2102078..2103037 (-) 960 WP_001253300.1 carbohydrate kinase -
  HLV54_RS10445 (HLV54_002089) - 2103034..2104518 (-) 1485 WP_000141422.1 sucrose-6-phosphate hydrolase -
  HLV54_RS10450 (HLV54_002090) - 2104667..2105617 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=594883 HLV54_RS10430 WP_000688492.1 2100995..2101711(+) (agrA) [Staphylococcus aureus strain HL23187]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=594883 HLV54_RS10430 WP_000688492.1 2100995..2101711(+) (agrA) [Staphylococcus aureus strain HL23187]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1