Detailed information NTG0059485

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SABB_RS10735
• Genome accession: NC_021670
• Coordinates: 2110144..2111187 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2105144..2116187

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SABB_RS10705 (SABB_02304)	-	2105562..2106818 (-)	1257	WP_001795438.1	aminopeptidase	-
SABB_RS10710 (SABB_02305)	-	2106821..2107021 (-)	201	WP_000180461.1	DUF1128 family protein	-
SABB_RS10715 (SABB_02306)	-	2107168..2107632 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SABB_RS10720 (SABB_02307)	-	2107639..2107914 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SABB_RS10725 (SABB_02308)	-	2108192..2109409 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SABB_RS10730 (SABB_03965)	vraR	2109525..2110154 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
SABB_RS10735 (SABB_02310)	vraS	2110144..2111187 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SABB_RS10740 (SABB_03226)	liaF	2111184..2111885 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SABB_RS10745 (SABB_02749)	-	2111900..2112286 (-)	387	WP_001110179.1	hypothetical protein	-
SABB_RS10750 (SABB_02313)	map	2112503..2113261 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SABB_RS10755 (SABB_02314)	-	2113733..2114719 (+)	987	WP_000999713.1	FUSC family protein	-
SABB_RS10765 (SABB_02315)	-	2115150..2115563 (-)	414	WP_001549145.1	hypothetical protein	-
SABB_RS10770	-	2115592..2115702 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=59485 SABB_RS10735 WP_001017131.1 2110144..2111187(-) (vraS) [Staphylococcus aureus]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=59485 SABB_RS10735 WP_001017131.1 2110144..2111187(-) (vraS) [Staphylococcus aureus]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1