Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M7750_RS01185 Genome accession   NZ_CP097363
Coordinates   240723..241379 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain AGR6137     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 235723..246379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M7750_RS01155 (M7750_01155) dcyD 236602..237588 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M7750_RS01160 (M7750_01160) tcyL 237603..238271 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M7750_RS01165 (M7750_01165) tcyN 238268..239020 (+) 753 WP_032167552.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M7750_RS01170 (M7750_01170) sdiA 239250..239972 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  M7750_RS01175 (M7750_01175) yecF 240040..240264 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M7750_RS01180 (M7750_01180) yecU 240251..240427 (-) 177 WP_000590347.1 protein YecU -
  M7750_RS01185 (M7750_01185) letA 240723..241379 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M7750_RS01190 (M7750_01190) uvrC 241376..243208 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M7750_RS01195 (M7750_01195) pgsA 243265..243813 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M7750_RS01215 (M7750_01215) yecA 244463..245128 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=594514 M7750_RS01185 WP_000611328.1 240723..241379(+) (letA) [Escherichia coli strain AGR6137]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=594514 M7750_RS01185 WP_000611328.1 240723..241379(+) (letA) [Escherichia coli strain AGR6137]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482