Detailed information NTG0594045

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JMO07_RS13080
• Genome accession: NZ_CP080564
• Coordinates: 2655934..2656821 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain HL16278
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2650934..2661821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO07_RS13050 (JMO07_002615)	-	2650952..2651044 (+)	93	WP_010956583.1	hypothetical protein	-
JMO07_RS13055 (JMO07_002616)	-	2651152..2651649 (-)	498	WP_001065269.1	glutathione peroxidase	-
JMO07_RS13060 (JMO07_002617)	-	2651659..2651919 (-)	261	WP_001789910.1	hypothetical protein	-
JMO07_RS13065 (JMO07_002618)	-	2652301..2652414 (-)	114	Protein_2557	hypothetical protein	-
JMO07_RS13070 (JMO07_002619)	-	2653073..2655073 (-)	2001	WP_000776739.1	ABC transporter permease	-
JMO07_RS13075 (JMO07_002620)	-	2655070..2655825 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JMO07_RS13080 (JMO07_002621)	braS	2655934..2656821 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JMO07_RS13085 (JMO07_002622)	braR	2656832..2657497 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JMO07_RS13090 (JMO07_002623)	-	2657523..2657723 (-)	201	WP_000604727.1	hypothetical protein	-
JMO07_RS13095 (JMO07_002624)	-	2657921..2659345 (+)	1425	WP_000953762.1	alkaline phosphatase	-
JMO07_RS13730	-	2659405..2659506 (-)	102	WP_000731972.1	SE2200 family small protein	-
JMO07_RS13105 (JMO07_002626)	-	2659628..2660083 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JMO07_RS13110 (JMO07_002627)	-	2660328..2661089 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=594045 JMO07_RS13080 WP_000143420.1 2655934..2656821(-) (braS) [Staphylococcus aureus strain HL16278]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=594045 JMO07_RS13080 WP_000143420.1 2655934..2656821(-) (braS) [Staphylococcus aureus strain HL16278]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993