Detailed information NTG0594001

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JMO08_RS14365
• Genome accession: NZ_CP080562
• Coordinates: 2845323..2846210 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain HL21008
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2840323..2851210

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO08_RS14335 (JMO08_002867)	-	2840342..2840434 (+)	93	WP_010956583.1	hypothetical protein	-
JMO08_RS14340 (JMO08_002868)	-	2840542..2841039 (-)	498	WP_001065268.1	glutathione peroxidase	-
JMO08_RS14345 (JMO08_002869)	-	2841049..2841309 (-)	261	WP_001791974.1	hypothetical protein	-
JMO08_RS14350 (JMO08_002870)	-	2841691..2841804 (-)	114	Protein_2803	hypothetical protein	-
JMO08_RS14355 (JMO08_002871)	-	2842463..2844463 (-)	2001	WP_000776751.1	ABC transporter permease	-
JMO08_RS14360 (JMO08_002872)	-	2844460..2845215 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JMO08_RS14365 (JMO08_002873)	braS	2845323..2846210 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JMO08_RS14370 (JMO08_002874)	braR	2846221..2846886 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JMO08_RS14375 (JMO08_002875)	-	2846912..2847112 (-)	201	WP_000604730.1	hypothetical protein	-
JMO08_RS14380 (JMO08_002876)	-	2847310..2848734 (+)	1425	WP_000953755.1	alkaline phosphatase	-
JMO08_RS15180	-	2848794..2848895 (-)	102	WP_000731976.1	SE2200 family small protein	-
JMO08_RS14390 (JMO08_002878)	-	2849017..2849472 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JMO08_RS14395 (JMO08_002879)	-	2849717..2850478 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=594001 JMO08_RS14365 WP_000143425.1 2845323..2846210(-) (braS) [Staphylococcus aureus strain HL21008]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=594001 JMO08_RS14365 WP_000143425.1 2845323..2846210(-) (braS) [Staphylococcus aureus strain HL21008]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1