Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JMO08_RS10950 Genome accession   NZ_CP080562
Coordinates   2182966..2183748 (+) Length   260 a.a.
NCBI ID   WP_220332215.1    Uniprot ID   -
Organism   Staphylococcus aureus strain HL21008     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2177966..2188748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMO08_RS10920 (JMO08_002184) - 2178183..2178809 (+) 627 WP_000522381.1 nitroreductase family protein -
  JMO08_RS10925 (JMO08_002185) - 2179170..2179955 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  JMO08_RS15150 hld 2180555..2180635 (-) 81 WP_000046022.1 delta-hemolysin -
  JMO08_RS10935 (JMO08_002187) - 2180925..2181488 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  JMO08_RS10940 (JMO08_002188) agrD 2181491..2181634 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  JMO08_RS10945 (JMO08_002189) agrC 2181664..2182947 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  JMO08_RS10950 (JMO08_002190) agrA 2182966..2183748 (+) 783 WP_220332215.1 quorum-sensing response regulator AgrA Regulator
  JMO08_RS10955 (JMO08_002191) - 2183756..2183865 (+) 110 Protein_2131 hypothetical protein -
  JMO08_RS10960 (JMO08_002192) - 2184053..2185012 (-) 960 WP_001253312.1 carbohydrate kinase -
  JMO08_RS10965 (JMO08_002193) - 2185009..2186493 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  JMO08_RS10970 (JMO08_002194) - 2186642..2187592 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 30425.87 Da        Isoelectric Point: 7.1168

>NTDB_id=593997 JMO08_RS10950 WP_220332215.1 2182966..2183748(+) (agrA) [Staphylococcus aureus strain HL21008]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKNNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKNNN
KIIKSVNGVFNCKSCWILTR

Nucleotide


Download         Length: 783 bp        

>NTDB_id=593997 JMO08_RS10950 WP_220332215.1 2182966..2183748(+) (agrA) [Staphylococcus aureus strain HL21008]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAAATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAATAATAAT
AAGATAATAAAGTCAGTTAACGGCGTATTCAATTGTAAATCTTGTTGGATTTTAACAAGATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.578

91.154

0.908