Detailed information NTG0593957

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JMO09_RS14235
• Genome accession: NZ_CP080560
• Coordinates: 2828862..2829749 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain HL17064
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2823862..2834749

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO09_RS14205 (JMO09_002841)	-	2823881..2823973 (+)	93	WP_010956583.1	hypothetical protein	-
JMO09_RS14210 (JMO09_002842)	-	2824081..2824578 (-)	498	WP_220374353.1	glutathione peroxidase	-
JMO09_RS14215 (JMO09_002843)	-	2824588..2824848 (-)	261	WP_001791974.1	hypothetical protein	-
JMO09_RS14220 (JMO09_002844)	-	2825230..2825343 (-)	114	Protein_2779	hypothetical protein	-
JMO09_RS14225 (JMO09_002845)	-	2826002..2828002 (-)	2001	WP_000776751.1	ABC transporter permease	-
JMO09_RS14230 (JMO09_002846)	-	2827999..2828754 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JMO09_RS14235 (JMO09_002847)	braS	2828862..2829749 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JMO09_RS14240 (JMO09_002848)	braR	2829760..2830425 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JMO09_RS14245 (JMO09_002849)	-	2830451..2830651 (-)	201	WP_000604730.1	hypothetical protein	-
JMO09_RS14250 (JMO09_002850)	-	2830849..2832273 (+)	1425	WP_000953755.1	alkaline phosphatase	-
JMO09_RS15060	-	2832333..2832434 (-)	102	WP_000731976.1	SE2200 family small protein	-
JMO09_RS14260 (JMO09_002852)	-	2832556..2833011 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JMO09_RS14265 (JMO09_002853)	-	2833256..2834017 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=593957 JMO09_RS14235 WP_000143425.1 2828862..2829749(-) (braS) [Staphylococcus aureus strain HL17064]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=593957 JMO09_RS14235 WP_000143425.1 2828862..2829749(-) (braS) [Staphylococcus aureus strain HL17064]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1