Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JMO09_RS11130 Genome accession   NZ_CP080560
Coordinates   2210743..2211459 (+) Length   238 a.a.
NCBI ID   WP_000688493.1    Uniprot ID   G9IE49
Organism   Staphylococcus aureus strain HL17064     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2205743..2216459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMO09_RS11100 (JMO09_002220) - 2205960..2206586 (+) 627 WP_000522381.1 nitroreductase family protein -
  JMO09_RS11105 (JMO09_002221) - 2206947..2207732 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  JMO09_RS15035 hld 2208332..2208412 (-) 81 WP_000046022.1 delta-hemolysin -
  JMO09_RS11115 (JMO09_002223) - 2208702..2209265 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  JMO09_RS11120 (JMO09_002224) agrD 2209268..2209411 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  JMO09_RS11125 (JMO09_002225) agrC 2209441..2210724 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  JMO09_RS11130 (JMO09_002226) agrA 2210743..2211459 (+) 717 WP_000688493.1 quorum-sensing response regulator AgrA Regulator
  JMO09_RS11135 (JMO09_002227) - 2211534..2211643 (+) 110 Protein_2170 hypothetical protein -
  JMO09_RS11140 (JMO09_002228) - 2211831..2212790 (-) 960 WP_001253312.1 carbohydrate kinase -
  JMO09_RS11145 (JMO09_002229) - 2212787..2214271 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  JMO09_RS11150 (JMO09_002230) - 2214420..2215370 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27920.92 Da        Isoelectric Point: 6.3009

>NTDB_id=593953 JMO09_RS11130 WP_000688493.1 2210743..2211459(+) (agrA) [Staphylococcus aureus strain HL17064]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKK

Nucleotide


Download         Length: 717 bp        

>NTDB_id=593953 JMO09_RS11130 WP_000688493.1 2210743..2211459(+) (agrA) [Staphylococcus aureus strain HL17064]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAAATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-236)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G9IE49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

99.58

0.996