Detailed information NTG0593912

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JMO10_RS14285
• Genome accession: NZ_CP080556
• Coordinates: 2818719..2819606 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain HL17078
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2813719..2824606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO10_RS14255 (JMO10_002852)	-	2813738..2813830 (+)	93	WP_010956583.1	hypothetical protein	-
JMO10_RS14260 (JMO10_002853)	-	2813938..2814435 (-)	498	WP_001065268.1	glutathione peroxidase	-
JMO10_RS14265 (JMO10_002854)	-	2814445..2814705 (-)	261	WP_001789910.1	hypothetical protein	-
JMO10_RS14270 (JMO10_002855)	-	2815087..2815200 (-)	114	WP_001791776.1	hypothetical protein	-
JMO10_RS14275 (JMO10_002856)	-	2815859..2817859 (-)	2001	WP_000776751.1	ABC transporter permease	-
JMO10_RS14280 (JMO10_002857)	-	2817856..2818611 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JMO10_RS14285 (JMO10_002858)	braS	2818719..2819606 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JMO10_RS14290 (JMO10_002859)	braR	2819617..2820282 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JMO10_RS14295 (JMO10_002860)	-	2820308..2820508 (-)	201	WP_000604728.1	hypothetical protein	-
JMO10_RS14300 (JMO10_002861)	-	2820706..2822130 (+)	1425	WP_000953744.1	alkaline phosphatase	-
JMO10_RS15260	-	2822190..2822291 (-)	102	WP_000731972.1	SE2200 family small protein	-
JMO10_RS14310 (JMO10_002863)	-	2822413..2822868 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JMO10_RS14315 (JMO10_002864)	-	2823113..2823874 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=593912 JMO10_RS14285 WP_000143419.1 2818719..2819606(-) (braS) [Staphylococcus aureus strain HL17078]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=593912 JMO10_RS14285 WP_000143419.1 2818719..2819606(-) (braS) [Staphylococcus aureus strain HL17078]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997