Detailed information NTG0593869

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JMO11_RS14265
• Genome accession: NZ_CP080553
• Coordinates: 2813703..2814590 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain HL18380
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2808703..2819590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO11_RS14235 (JMO11_002842)	-	2808722..2808814 (+)	93	WP_010956583.1	hypothetical protein	-
JMO11_RS14240 (JMO11_002843)	-	2808922..2809419 (-)	498	WP_001065268.1	glutathione peroxidase	-
JMO11_RS14245 (JMO11_002844)	-	2809429..2809689 (-)	261	WP_001789910.1	hypothetical protein	-
JMO11_RS14250 (JMO11_002845)	-	2810071..2810184 (-)	114	WP_001791776.1	hypothetical protein	-
JMO11_RS14255 (JMO11_002846)	-	2810843..2812843 (-)	2001	WP_000776751.1	ABC transporter permease	-
JMO11_RS14260 (JMO11_002847)	-	2812840..2813595 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JMO11_RS14265 (JMO11_002848)	braS	2813703..2814590 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JMO11_RS14270 (JMO11_002849)	braR	2814601..2815266 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JMO11_RS14275 (JMO11_002850)	-	2815292..2815492 (-)	201	WP_000604728.1	hypothetical protein	-
JMO11_RS14280 (JMO11_002851)	-	2815690..2817114 (+)	1425	WP_000953744.1	alkaline phosphatase	-
JMO11_RS15035	-	2817174..2817275 (-)	102	WP_000731972.1	SE2200 family small protein	-
JMO11_RS14290 (JMO11_002853)	-	2817397..2817852 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JMO11_RS14295 (JMO11_002854)	-	2818097..2818858 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=593869 JMO11_RS14265 WP_000143419.1 2813703..2814590(-) (braS) [Staphylococcus aureus strain HL18380]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=593869 JMO11_RS14265 WP_000143419.1 2813703..2814590(-) (braS) [Staphylococcus aureus strain HL18380]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997