Detailed information NTG0593827

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JMO12_RS14080
• Genome accession: NZ_CP080552
• Coordinates: 2801622..2802509 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain HL18807
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2796622..2807509

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO12_RS14050 (JMO12_002811)	-	2796641..2796733 (+)	93	WP_010956583.1	hypothetical protein	-
JMO12_RS14055 (JMO12_002812)	-	2796841..2797338 (-)	498	WP_001065268.1	glutathione peroxidase	-
JMO12_RS14060 (JMO12_002813)	-	2797348..2797608 (-)	261	WP_001791974.1	hypothetical protein	-
JMO12_RS14065 (JMO12_002814)	-	2797990..2798103 (-)	114	Protein_2748	hypothetical protein	-
JMO12_RS14070 (JMO12_002815)	-	2798762..2800762 (-)	2001	WP_000776751.1	ABC transporter permease	-
JMO12_RS14075 (JMO12_002816)	-	2800759..2801514 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
JMO12_RS14080 (JMO12_002817)	braS	2801622..2802509 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JMO12_RS14085 (JMO12_002818)	braR	2802520..2803185 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JMO12_RS14090 (JMO12_002819)	-	2803211..2803411 (-)	201	WP_000604730.1	hypothetical protein	-
JMO12_RS14095 (JMO12_002820)	-	2803609..2805033 (+)	1425	WP_000953755.1	alkaline phosphatase	-
JMO12_RS14725	-	2805093..2805194 (-)	102	WP_000731976.1	SE2200 family small protein	-
JMO12_RS14105 (JMO12_002822)	-	2805316..2805771 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JMO12_RS14110 (JMO12_002823)	-	2806016..2806777 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=593827 JMO12_RS14080 WP_000143425.1 2801622..2802509(-) (braS) [Staphylococcus aureus strain HL18807]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=593827 JMO12_RS14080 WP_000143425.1 2801622..2802509(-) (braS) [Staphylococcus aureus strain HL18807]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1