Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JMO12_RS10965 Genome accession   NZ_CP080552
Coordinates   2183507..2184289 (+) Length   260 a.a.
NCBI ID   WP_084943916.1    Uniprot ID   -
Organism   Staphylococcus aureus strain HL18807     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2178507..2189289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMO12_RS10935 (JMO12_002189) - 2178724..2179350 (+) 627 WP_000522381.1 nitroreductase family protein -
  JMO12_RS10940 (JMO12_002190) - 2179711..2180496 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  JMO12_RS14705 hld 2181096..2181176 (-) 81 WP_000046022.1 delta-hemolysin -
  JMO12_RS10950 (JMO12_002192) - 2181466..2182029 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  JMO12_RS10955 (JMO12_002193) agrD 2182032..2182175 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  JMO12_RS10960 (JMO12_002194) agrC 2182205..2183488 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  JMO12_RS10965 (JMO12_002195) agrA 2183507..2184289 (+) 783 WP_084943916.1 quorum-sensing response regulator AgrA Regulator
  JMO12_RS10970 (JMO12_002196) - 2184297..2184406 (+) 110 Protein_2137 hypothetical protein -
  JMO12_RS10975 (JMO12_002197) - 2184594..2185553 (-) 960 WP_001253312.1 carbohydrate kinase -
  JMO12_RS10980 (JMO12_002198) - 2185550..2187034 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  JMO12_RS10985 (JMO12_002199) - 2187183..2188133 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 30426.85 Da        Isoelectric Point: 6.8881

>NTDB_id=593823 JMO12_RS10965 WP_084943916.1 2183507..2184289(+) (agrA) [Staphylococcus aureus strain HL18807]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKNNN
KIIKSVNGVFNCKSCWILTR

Nucleotide


Download         Length: 783 bp        

>NTDB_id=593823 JMO12_RS10965 WP_084943916.1 2183507..2184289(+) (agrA) [Staphylococcus aureus strain HL18807]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAATAATAAT
AAGATAATAAAGTCAGTTAACGGCGTATTCAATTGTAAATCTTGTTGGATTTTAACAAGATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

91.154

0.912