Detailed information NTG0593783

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: JMO13_RS13395
• Genome accession: NZ_CP080551
• Coordinates: 2695735..2696622 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain HL18840
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2690735..2701622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO13_RS13365 (JMO13_002673)	-	2690754..2690846 (+)	93	WP_010956583.1	hypothetical protein	-
JMO13_RS13370 (JMO13_002674)	-	2690954..2691451 (-)	498	WP_001065269.1	glutathione peroxidase	-
JMO13_RS13375 (JMO13_002675)	-	2691461..2691721 (-)	261	WP_001789910.1	hypothetical protein	-
JMO13_RS13380 (JMO13_002676)	-	2692103..2692216 (-)	114	Protein_2619	hypothetical protein	-
JMO13_RS13385 (JMO13_002677)	-	2692875..2694875 (-)	2001	WP_000776739.1	ABC transporter permease	-
JMO13_RS13390 (JMO13_002678)	-	2694872..2695626 (-)	755	Protein_2621	ABC transporter ATP-binding protein	-
JMO13_RS13395 (JMO13_002679)	braS	2695735..2696622 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
JMO13_RS13400 (JMO13_002680)	braR	2696633..2697298 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
JMO13_RS13405 (JMO13_002681)	-	2697324..2697524 (-)	201	WP_000604727.1	hypothetical protein	-
JMO13_RS13410 (JMO13_002682)	-	2697722..2699146 (+)	1425	WP_000953762.1	alkaline phosphatase	-
JMO13_RS14040	-	2699206..2699307 (-)	102	WP_000731972.1	SE2200 family small protein	-
JMO13_RS13420 (JMO13_002684)	-	2699429..2699884 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
JMO13_RS13425 (JMO13_002685)	-	2700129..2700890 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=593783 JMO13_RS13395 WP_000143420.1 2695735..2696622(-) (braS) [Staphylococcus aureus strain HL18840]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=593783 JMO13_RS13395 WP_000143420.1 2695735..2696622(-) (braS) [Staphylococcus aureus strain HL18840]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993