Detailed information NTG0593777

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JMO13_RS09560
• Genome accession: NZ_CP080551
• Coordinates: 1953375..1954418 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain HL18840
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1948375..1959418

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO13_RS09530 (JMO13_001907)	-	1948797..1950053 (-)	1257	WP_001789555.1	aminopeptidase	-
JMO13_RS09535 (JMO13_001908)	-	1950056..1950256 (-)	201	WP_000180460.1	DUF1128 family protein	-
JMO13_RS09540 (JMO13_001909)	-	1950403..1950867 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
JMO13_RS09545 (JMO13_001910)	-	1950874..1951149 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JMO13_RS09550 (JMO13_001911)	-	1951427..1952644 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
JMO13_RS09555 (JMO13_001912)	vraR	1952756..1953385 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
JMO13_RS09560 (JMO13_001913)	vraS	1953375..1954418 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JMO13_RS09565 (JMO13_001914)	liaF	1954415..1955116 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JMO13_RS09570 (JMO13_001915)	-	1955131..1955517 (-)	387	WP_001110179.1	hypothetical protein	-
JMO13_RS09575 (JMO13_001916)	map	1955734..1956492 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
JMO13_RS09580 (JMO13_001917)	-	1957020..1958006 (+)	987	WP_000999714.1	aromatic acid exporter family protein	-
JMO13_RS09585 (JMO13_001918)	-	1958437..1958850 (-)	414	WP_025173836.1	hypothetical protein	-
JMO13_RS09590 (JMO13_001919)	-	1958879..1958989 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=593777 JMO13_RS09560 WP_001017131.1 1953375..1954418(-) (vraS) [Staphylococcus aureus strain HL18840]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=593777 JMO13_RS09560 WP_001017131.1 1953375..1954418(-) (vraS) [Staphylococcus aureus strain HL18840]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1