Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   JMO13_RS00200 Genome accession   NZ_CP080551
Coordinates   46976..48325 (-) Length   449 a.a.
NCBI ID   WP_002486033.1    Uniprot ID   -
Organism   Staphylococcus aureus strain HL18840     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 37001..53496 46976..48325 within 0


Gene organization within MGE regions


Location: 37001..53496
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JMO13_RS00155 (JMO13_000031) mecA 37001..39010 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  JMO13_RS00160 (JMO13_000032) - 39107..40093 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  JMO13_RS00165 (JMO13_000033) - 40080..40325 (+) 246 Protein_30 type I restriction enzyme endonuclease domain-containing protein -
  JMO13_RS00170 (JMO13_000034) - 40592..41791 (+) 1200 WP_073392450.1 IS110-like element ISSep2 family transposase -
  JMO13_RS00175 (JMO13_000035) - 41888..43486 (-) 1599 Protein_32 IS1182 family transposase -
  JMO13_RS00180 (JMO13_000036) - 43535..44041 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  JMO13_RS00185 (JMO13_000037) - 44056..44367 (-) 312 WP_000700851.1 DUF960 family protein -
  JMO13_RS00190 (JMO13_000038) - 44454..44804 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  JMO13_RS00195 (JMO13_000039) ccrB 45326..46954 (-) 1629 WP_001186608.1 cassette chromosome recombinase CcrB Machinery gene
  JMO13_RS00200 (JMO13_000040) ccrA 46976..48325 (-) 1350 WP_002486033.1 cassette chromosome recombinase CcrA Machinery gene
  JMO13_RS00205 (JMO13_000041) cch1 48559..50352 (-) 1794 WP_000079474.1 cassette chromosome replicative helicase -
  JMO13_RS00210 (JMO13_000042) ssb 50352..50648 (-) 297 WP_000273823.1 cassette chromosome ssDNA-binding protein -
  JMO13_RS00215 (JMO13_000043) - 50841..51887 (-) 1047 WP_001042023.1 hypothetical protein -
  JMO13_RS00220 (JMO13_000044) - 52342..53496 (+) 1155 WP_000912116.1 ATP-binding protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52614.32 Da        Isoelectric Point: 9.9100

>NTDB_id=593744 JMO13_RS00200 WP_002486033.1 46976..48325(-) (ccrA) [Staphylococcus aureus strain HL18840]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQLTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQTKQTSSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDQHIYVKIKNAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFRKQMQSLHQQPQRITSISEHQIQHTIQ
NIIQKRFTLNILYPYIETIHIAKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=593744 JMO13_RS00200 WP_002486033.1 46976..48325(-) (ccrA) [Staphylococcus aureus strain HL18840]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAATTAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAATATGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAAAAGTG
TGCCAAGACTTTTATCAAGACCAACATATCTACGTAAAAATTAAAAATGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAGCATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTTA
GAAAACAAATGCAATCATTACATCAACAACCACAACGCATCACATCCATCAGTGAGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTGCGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(169-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

95.546

100

0.955
  ccrA Staphylococcus aureus COL

74.833

100

0.748