Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CA347_RS10890 Genome accession   NC_021554
Coordinates   2140903..2141682 (+) Length   259 a.a.
NCBI ID   WP_000688495.1    Uniprot ID   -
Organism   Staphylococcus aureus CA-347     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2135903..2146682
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA347_RS10860 (CA347_2105) - 2136119..2136745 (+) 627 WP_000522375.1 nitroreductase family protein -
  CA347_RS10865 (CA347_2106) - 2137106..2137891 (+) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  CA347_RS15780 hld 2138492..2138572 (-) 81 WP_000046022.1 delta-hemolysin -
  CA347_RS10875 (CA347_2108) agrB 2138861..2139430 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  CA347_RS10880 (CA347_2109) agrD 2139427..2139567 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  CA347_RS10885 (CA347_2110) agrC 2139592..2140884 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  CA347_RS10890 (CA347_2111) agrA 2140903..2141682 (+) 780 WP_000688495.1 quorum-sensing response regulator AgrA Regulator
  CA347_RS10895 - 2141690..2141797 (+) 108 WP_031785433.1 hypothetical protein -
  CA347_RS10900 (CA347_2112) - 2141987..2142946 (-) 960 WP_001253295.1 carbohydrate kinase family protein -
  CA347_RS10905 (CA347_2113) - 2142943..2144427 (-) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  CA347_RS10910 (CA347_2114) - 2144576..2145526 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 30361.82 Da        Isoelectric Point: 6.8880

>NTDB_id=59329 CA347_RS10890 WP_000688495.1 2140903..2141682(+) (agrA) [Staphylococcus aureus CA-347]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKYNK
IIKSVNGVFNCKSCWILTR

Nucleotide


Download         Length: 780 bp        

>NTDB_id=59329 CA347_RS10890 WP_000688495.1 2140903..2141682(+) (agrA) [Staphylococcus aureus CA-347]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAATATAATAAG
ATAATAAAGTCAGTTAACGGCGTATTCAATTGTAAATCTTGTTGGATTTTAACAAGATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-242)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

91.506

0.915

Multiple sequence alignment