Detailed information NTG0591691

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KZW86_RS14400
• Genome accession: NZ_CP080249
• Coordinates: 2837699..2838586 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain NV_1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2832699..2843586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KZW86_RS14370 (KZW86_14270)	-	2832718..2832810 (+)	93	WP_010956583.1	hypothetical protein	-
KZW86_RS14375 (KZW86_14275)	-	2832918..2833415 (-)	498	WP_001065268.1	glutathione peroxidase	-
KZW86_RS14380 (KZW86_14280)	-	2833425..2833685 (-)	261	WP_001791974.1	hypothetical protein	-
KZW86_RS14385 (KZW86_14285)	-	2834067..2834180 (-)	114	Protein_2801	hypothetical protein	-
KZW86_RS14390 (KZW86_14290)	-	2834839..2836839 (-)	2001	WP_000776751.1	ABC transporter permease	-
KZW86_RS14395 (KZW86_14295)	-	2836836..2837591 (-)	756	WP_234718454.1	ABC transporter ATP-binding protein	-
KZW86_RS14400 (KZW86_14300)	braS	2837699..2838586 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KZW86_RS14405 (KZW86_14305)	braR	2838597..2839262 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KZW86_RS14410 (KZW86_14310)	-	2839288..2839488 (-)	201	WP_000604730.1	hypothetical protein	-
KZW86_RS14415 (KZW86_14315)	-	2839686..2841110 (+)	1425	WP_000953755.1	alkaline phosphatase	-
KZW86_RS15045	-	2841170..2841271 (-)	102	WP_000731976.1	SE2200 family small protein	-
KZW86_RS14425 (KZW86_14325)	-	2841393..2841848 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KZW86_RS14430 (KZW86_14330)	-	2842093..2842854 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=591691 KZW86_RS14400 WP_000143425.1 2837699..2838586(-) (braS) [Staphylococcus aureus strain NV_1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=591691 KZW86_RS14400 WP_000143425.1 2837699..2838586(-) (braS) [Staphylococcus aureus strain NV_1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1