Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   KZH43_RS08945 Genome accession   NZ_CP079923
Coordinates   1774794..1775804 (-) Length   336 a.a.
NCBI ID   WP_000990607.1    Uniprot ID   A0A0B7LZL8
Organism   Streptococcus pneumoniae strain Rx1     
Function   regulate comCDE transcription and transformation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1769794..1780804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZH43_RS08915 (KZH43_08910) - 1769814..1771028 (-) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  KZH43_RS08920 (KZH43_08915) - 1771184..1771477 (-) 294 WP_000977365.1 hypothetical protein -
  KZH43_RS08925 (KZH43_08920) - 1771639..1772091 (+) 453 WP_000079154.1 universal stress protein -
  KZH43_RS08930 (KZH43_08925) - 1772126..1773514 (-) 1389 WP_000453139.1 Cof-type HAD-IIB family hydrolase -
  KZH43_RS08935 (KZH43_08930) - 1773580..1774542 (+) 963 WP_001124777.1 asparaginase -
  KZH43_RS08940 (KZH43_08935) - 1774539..1774730 (-) 192 WP_001092029.1 hypothetical protein -
  KZH43_RS08945 (KZH43_08940) ccpA 1774794..1775804 (-) 1011 WP_000990607.1 catabolite control protein A Regulator
  KZH43_RS08950 (KZH43_08945) - 1776229..1776828 (-) 600 WP_000866719.1 response regulator transcription factor -
  KZH43_RS08955 (KZH43_08950) - 1776830..1777927 (-) 1098 WP_000893546.1 sensor histidine kinase -
  KZH43_RS08960 (KZH43_08955) - 1777927..1778664 (-) 738 WP_000832834.1 ABC transporter permease -
  KZH43_RS08965 (KZH43_08960) - 1778666..1779550 (-) 885 WP_000219348.1 ABC transporter ATP-binding protein -
  KZH43_RS08970 (KZH43_08965) - 1779537..1779731 (-) 195 WP_000820180.1 hypothetical protein -
  KZH43_RS08975 (KZH43_08970) - 1779728..1779934 (-) 207 WP_000503437.1 hypothetical protein -

Sequence

Protein


Download         Length: 336 a.a.        Molecular weight: 37073.01 Da        Isoelectric Point: 5.3212

>NTDB_id=590194 KZH43_RS08945 WP_000990607.1 1774794..1775804(-) (ccpA) [Streptococcus pneumoniae strain Rx1]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide


Download         Length: 1011 bp        

>NTDB_id=590194 KZH43_RS08945 WP_000990607.1 1774794..1775804(-) (ccpA) [Streptococcus pneumoniae strain Rx1]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, lacI family (LacI)

(8-53)

Periplasmic binding protein-like domain (Peripla_BP_3)

(181-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7LZL8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus pneumoniae D39

99.702

100

0.997
  ccpA Streptococcus gordonii str. Challis substr. CH1

87.126

99.405

0.866
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

57.704

98.512

0.568