Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   LPB404_RS03565 Genome accession   NZ_CP079821
Coordinates   698136..700403 (-) Length   755 a.a.
NCBI ID   WP_219075055.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 693136..705403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS03545 (LPB404_03545) ileS 693688..696480 (+) 2793 WP_219075052.1 isoleucine--tRNA ligase -
  LPB404_RS03550 (LPB404_03550) - 696542..696976 (+) 435 WP_219075053.1 GNAT family N-acetyltransferase -
  LPB404_RS03555 (LPB404_03555) - 697058..697360 (-) 303 WP_006596776.1 DUF1827 family protein -
  LPB404_RS03560 (LPB404_03560) - 697428..697877 (-) 450 WP_219075054.1 NUDIX hydrolase -
  LPB404_RS03565 (LPB404_03565) clpE 698136..700403 (-) 2268 WP_219075055.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  LPB404_RS03570 (LPB404_03570) - 700633..700863 (+) 231 WP_006596773.1 DUF1797 family protein -
  LPB404_RS03575 (LPB404_03575) - 701174..702028 (+) 855 WP_219075056.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  LPB404_RS03580 (LPB404_03580) - 702162..703004 (+) 843 WP_219075057.1 NAD(P)H-hydrate dehydratase -
  LPB404_RS03585 (LPB404_03585) xseA 703129..704469 (+) 1341 WP_219075058.1 exodeoxyribonuclease VII large subunit -
  LPB404_RS03590 (LPB404_03590) - 704447..704659 (+) 213 WP_006596769.1 exodeoxyribonuclease VII small subunit -

Sequence

Protein


Download         Length: 755 a.a.        Molecular weight: 83880.02 Da        Isoelectric Point: 4.9761

>NTDB_id=589754 LPB404_RS03565 WP_219075055.1 698136..700403(-) (clpE) [Streptococcus rubneri strain LPB0404]
MLCQNCKINDSTIHLYTNVNGHQQQVDLCQNCYQIMKTDPNNSLLAGLNQQNRGGRDPFEDFFNQLGNFQAPQEPQTPPT
QSGGGYGGGNGYGQNGNGRATGPNRPQAKQQPKGLLEEFGINVTEIARRGDIDPVIGRDDEILRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPYKLQGKEVIRLDVVSLVQGTGIRGQFEERMQQLMEEIRRREDVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYT
DGAIEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKY
KEMQGQQVTDQDTPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLAADLKAHVIGQDEAVEKIAKAIRRNRVGLGTPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSILGELGNFFSPEFM
NRFDGIIEFKALSKENLLQIVTLMLDDVNQRLAHNDIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYL
ENPSEKDLKAVMTSNGKICIKGKTKPANEAEKVTE

Nucleotide


Download         Length: 2268 bp        

>NTDB_id=589754 LPB404_RS03565 WP_219075055.1 698136..700403(-) (clpE) [Streptococcus rubneri strain LPB0404]
ATGCTTTGTCAAAACTGTAAAATAAACGATTCAACCATTCATCTTTATACGAATGTGAATGGTCACCAACAACAAGTAGA
CCTTTGCCAGAACTGCTATCAAATTATGAAAACCGATCCTAACAATAGTCTCCTGGCAGGATTAAACCAACAAAATCGCG
GAGGGCGGGATCCTTTTGAAGATTTCTTCAATCAACTGGGCAACTTCCAAGCTCCCCAAGAACCTCAAACGCCACCGACC
CAATCAGGAGGAGGCTATGGGGGTGGAAATGGCTACGGACAAAATGGGAACGGTCGAGCTACTGGACCAAATAGACCTCA
AGCCAAACAACAACCGAAAGGACTCCTAGAAGAGTTTGGAATTAATGTTACTGAAATCGCTCGCCGTGGGGACATTGATC
CAGTCATTGGCCGTGACGACGAAATTCTCCGAGTTATTGAAATTTTAAACCGCCGAACCAAAAACAACCCTGTTCTGATT
GGAGAACCTGGTGTCGGAAAAACAGCTGTCGTAGAAGGCCTGGCCCAGAAGATTGTCGATGGCGATGTCCCTTATAAATT
ACAAGGCAAGGAAGTCATTCGTCTAGACGTTGTTAGCCTCGTTCAAGGGACTGGGATTCGTGGACAATTTGAAGAACGGA
TGCAACAATTAATGGAAGAAATCCGTCGGCGGGAAGATGTGATTTTGTTTATCGATGAAATCCATGAAATTGTAGGAGCA
GGATCTGCAGGTGATGGCAACATGGATGCAGGAAACATCCTCAAACCGGCTCTCGCTCGTGGTGAATTGCAATTAGTCGG
TGCCACAACACTCAATGAGTATCGTATTATCGAAAAAGATGCCGCTCTTGAACGCCGGATGCAACCAGTCAAGGTGGATG
AACCAACGGTTGAAGAAACCATTACCATCCTTAAAGGCATTCAAAAGAAATACGAAGACTACCACCACGTCCACTACACA
GATGGTGCAATAGAAGCTGCAGCACTCCTCTCCAATCGCTATATCCAAGACCGCTTCTTGCCCGACAAGGCCATTGACCT
CTTGGACGAAGCAGGCTCTAAGATGAATTTGACCCTCAATTTTGTCGATCCCAAAGTCATTGACCAGCGCTTAATTGAAG
CCGAAAATCTCAAGGCCCAAGCGACGCGGGATGAAGACTTCGAAAAAGCAGCCTACTTCCGTGACCAAATCGCTAAGTAC
AAAGAAATGCAAGGGCAACAGGTCACCGACCAAGATACGCCCGTCATTAGCGAAAAGACTATCGAACATATTGTCGAGCA
AAAGACCAATATTCCAGTTGGAGATTTGAAAGAAAAAGAACAGTCTCAATTGATTAATTTGGCTGCTGATTTAAAAGCTC
ATGTCATCGGCCAAGATGAGGCTGTTGAAAAAATTGCTAAGGCTATCCGTCGTAATCGGGTAGGACTTGGAACGCCAAAC
CGTCCAATCGGTAGCTTCCTCTTTGTTGGACCAACTGGTGTCGGGAAGACCGAGTTGTCCAAGCAATTGGCCATCGAACT
CTTCGGTTCTGCTGACAGTATGATTCGCTTTGACATGAGCGAATACATGGAGAAACATGCCGTTGCCAAATTGGTCGGTG
CCCCTCCAGGCTACGTTGGCTATGAAGAAGCTGGTCAGCTGACTGAAAAAGTACGTCGCAACCCTTACTCTCTTATTCTT
CTAGATGAGGTAGAAAAGGCCCATCCTGATGTCATGCATATGTTCCTTCAAGTCTTAGATGATGGTCGCTTGACAGATGG
TCAAGGACGAACAGTGAGCTTCAAAGATACCATTATCATCATGACTTCCAATGCGGGAACTGGAAAAGCGGAGGCTAACG
TCGGTTTTGGGGCAGCTCGTGAAGGTCGTACCAATTCGATCCTAGGTGAACTTGGAAACTTCTTTAGTCCAGAATTCATG
AACCGGTTTGATGGTATTATTGAATTCAAAGCCTTGTCTAAGGAAAACCTCCTTCAAATCGTCACTCTTATGCTCGATGA
TGTCAATCAACGCCTGGCCCACAATGATATTCACCTCGATGTTACCGATAAGGTCAAGGAAAAATTGGTTGATTTGGGCT
ACGATCCGAAAATGGGAGCTCGTCCTCTTCGACGCACCATTCAAGACTATATCGAAGATGCCATTACAGATTACTACCTA
GAAAATCCTAGTGAAAAAGATCTGAAGGCTGTCATGACCAGCAATGGAAAGATTTGCATTAAAGGAAAGACCAAACCTGC
AAACGAGGCAGAAAAAGTAACTGAATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(296-393)

AAA domain (Cdc48 subfamily) (AAA_2)

(481-644)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(652-726)

ATPase family associated with various cellular activities (AAA) (AAA)

(158-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

87.169

100

0.873
  clpE Streptococcus pneumoniae D39

87.169

100

0.873
  clpE Streptococcus pneumoniae R6

87.169

100

0.873
  clpE Streptococcus pneumoniae TIGR4

87.169

100

0.873
  clpE Streptococcus mutans UA159

84.321

100

0.848
  clpC Lactococcus lactis subsp. cremoris KW2

76.455

100

0.766
  clpC Bacillus subtilis subsp. subtilis str. 168

50.661

90.199

0.457
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.644

83.046

0.404
  clpC Streptococcus pneumoniae Rx1

48.387

82.119

0.397
  clpC Streptococcus pneumoniae D39

48.387

82.119

0.397
  clpC Streptococcus pneumoniae TIGR4

48.226

82.119

0.396
  clpC Streptococcus thermophilus LMD-9

46.479

84.636

0.393
  clpC Streptococcus thermophilus LMG 18311

46.311

84.371

0.391
  clpC Streptococcus mutans UA159

47.504

82.252

0.391