Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   LPB404_RS03215 Genome accession   NZ_CP079821
Coordinates   640474..641772 (+) Length   432 a.a.
NCBI ID   WP_219075021.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 635474..646772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS03190 (LPB404_03190) - 635991..636623 (+) 633 WP_023022361.1 response regulator transcription factor -
  LPB404_RS03195 (LPB404_03195) - 636668..638074 (+) 1407 WP_219075020.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  LPB404_RS03200 (LPB404_03200) - 638071..638439 (+) 369 WP_120701187.1 S1 RNA-binding domain-containing protein -
  LPB404_RS03205 (LPB404_03205) cysK 638765..639694 (-) 930 WP_023027743.1 cysteine synthase A -
  LPB404_RS03210 (LPB404_03210) - 639786..640418 (-) 633 WP_023027744.1 YigZ family protein -
  LPB404_RS03215 (LPB404_03215) comFA/cflA 640474..641772 (+) 1299 WP_219075021.1 DEAD/DEAH box helicase Machinery gene
  LPB404_RS03220 (LPB404_03220) - 641835..642440 (+) 606 WP_257573063.1 ComF family protein -
  LPB404_RS03225 (LPB404_03225) hpf 642528..643073 (+) 546 WP_125375215.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49703.22 Da        Isoelectric Point: 9.7621

>NTDB_id=589751 LPB404_RS03215 WP_219075021.1 640474..641772(+) (comFA/cflA) [Streptococcus rubneri strain LPB0404]
MKVEDCYGRLFTQDQLEVELLGQAQRLPTMVEEKTGLLCNRCGSQIDKTRWKLQIGSYYCRACIQLGRVRSDQTLYHFPQ
EAFPQEEVLRWQGSLTPFQSRVSQELVQSLTDSKPMMVHAVTGAGKTEMMYQVVAEVIKKGRCVCIATPRIDVCIELYKR
MTKDFSCPISLLHGDSEPYFRTPLIISTTHQLLKFYQAFDLLIIDEVDAFPFVDNPVLYHAVSNAVTKKGKLIYLTATST
KELDKKVKKKEITRVSLPRRFHGNPLVIPKKVWLKDLRKKVEKRQVPGKLLRLIKKQRKTSFPLILFVSEIELGEKILKL
LRENFKDEIIELVTSKTENRLELVEKFRNQEITILVSTTILERGVTFPKVDVFVIEANHRLFTKSALVQISGRVGRSMER
PTGELLFLAEGSSQEMTQAIKEIKEMNREAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=589751 LPB404_RS03215 WP_219075021.1 640474..641772(+) (comFA/cflA) [Streptococcus rubneri strain LPB0404]
ATGAAAGTTGAAGATTGTTATGGAAGGTTGTTTACCCAAGATCAACTAGAGGTGGAGCTACTTGGACAAGCCCAGCGACT
GCCAACTATGGTAGAGGAAAAGACGGGTTTGCTTTGTAATCGTTGCGGAAGCCAGATTGATAAGACTAGATGGAAACTGC
AGATAGGAAGCTACTATTGTAGAGCTTGCATTCAATTAGGAAGAGTTAGGAGCGACCAAACACTCTATCACTTTCCCCAA
GAAGCTTTTCCCCAAGAAGAAGTCTTAAGATGGCAGGGGAGTCTGACACCATTTCAAAGTCGGGTTTCTCAAGAGTTGGT
TCAATCCTTAACAGATAGCAAGCCGATGATGGTACACGCAGTAACAGGAGCGGGTAAAACGGAAATGATGTACCAAGTGG
TGGCAGAAGTGATAAAAAAGGGGAGATGTGTTTGTATTGCTACACCAAGGATTGACGTGTGTATTGAATTGTATAAGCGA
ATGACAAAGGACTTTTCCTGCCCCATCTCCTTGTTGCACGGTGATTCAGAACCTTATTTCCGAACGCCTCTTATCATATC
CACCACTCATCAACTACTAAAGTTCTATCAAGCTTTTGACCTCCTCATCATCGATGAAGTCGATGCCTTTCCTTTTGTTG
ATAACCCTGTTCTCTACCATGCCGTTTCAAATGCCGTAACCAAGAAAGGGAAACTTATCTATTTGACAGCTACCTCTACA
AAAGAGTTAGATAAAAAGGTCAAAAAAAAGGAAATAACCCGCGTTAGCCTACCCAGGCGCTTTCACGGAAATCCTCTAGT
AATTCCTAAAAAAGTATGGCTAAAAGATCTACGAAAGAAAGTAGAAAAGAGGCAAGTACCAGGGAAGTTACTCAGACTAA
TAAAGAAACAACGAAAAACAAGCTTTCCACTGATCCTATTTGTATCAGAGATTGAATTAGGAGAAAAGATCCTTAAACTC
TTAAGAGAGAACTTCAAGGATGAAATCATCGAACTGGTGACCTCTAAAACAGAAAATAGATTGGAACTGGTAGAAAAATT
TCGCAACCAAGAAATTACCATCCTTGTTTCAACGACAATCCTGGAAAGGGGAGTCACCTTCCCTAAAGTAGATGTGTTTG
TGATTGAGGCCAATCATCGGCTGTTCACTAAGAGCGCACTGGTTCAAATATCTGGTCGTGTGGGAAGAAGTATGGAAAGA
CCTACAGGGGAATTGCTTTTCCTAGCAGAAGGAAGCAGCCAAGAAATGACACAAGCCATTAAAGAAATAAAAGAAATGAA
TCGGGAGGCAGGATTTTGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(95-238)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

62.818

100

0.63
  comFA/cflA Streptococcus pneumoniae D39

62.587

100

0.627
  comFA/cflA Streptococcus pneumoniae R6

62.587

100

0.627
  comFA/cflA Streptococcus pneumoniae TIGR4

62.587

100

0.627
  comFA/cflA Streptococcus pneumoniae Rx1

62.587

100

0.627
  comFA/cflA Streptococcus mitis SK321

61.894

100

0.62
  comFA Lactococcus lactis subsp. cremoris KW2

52.792

91.204

0.481
  comFA Latilactobacillus sakei subsp. sakei 23K

38.605

99.537

0.384