Detailed information NTG0589006

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: KX728_RS09030
• Genome accession: NZ_CP079724
• Coordinates: 1863889..1866321 (-)
• Length: 810 a.a.
• NCBI ID: WP_215804227.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain 34
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1858889..1871321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KX728_RS09005 (KX728_09000)	-	1859332..1860018 (-)	687	WP_215804231.1	YoaK family protein	-
KX728_RS09010 (KX728_09005)	-	1860145..1860828 (-)	684	WP_084877196.1	hypothetical protein	-
KX728_RS09015 (KX728_09010)	-	1861121..1861894 (-)	774	WP_215804230.1	NUDIX hydrolase	-
KX728_RS09020 (KX728_09015)	pnuC	1861896..1862675 (-)	780	WP_215804229.1	nicotinamide riboside transporter PnuC	-
KX728_RS09025 (KX728_09020)	-	1862685..1863743 (-)	1059	WP_215804228.1	AAA family ATPase	-
KX728_RS09030 (KX728_09025)	clpC	1863889..1866321 (-)	2433	WP_215804227.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
KX728_RS09035 (KX728_09030)	-	1866323..1866781 (-)	459	WP_215804226.1	CtsR family transcriptional regulator	-
KX728_RS09040 (KX728_09035)	-	1866953..1870738 (-)	3786	WP_223335667.1	Spy0128 family protein	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90260.12 Da
• Isoelectric Point: 6.0999

>NTDB_id=589006 KX728_RS09030 WP_215804227.1 1863889..1866321(-) (clpC) [Streptococcus oralis strain 34]
MNYSKALNECIESAYMVASHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVTDKQNSMANMMGMPQAQSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMVKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSLADSMTILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSGLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDLRFDQENMEKRIFEELKKAYRPEFINRIDEKVVFHSLDS
KHMQEIVKIMVKPLIASLAEKGIDLKLQASALKLLASQGYDPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKIGV
KAGQLKFDIA

Nucleotide

• Length: 2433 bp

>NTDB_id=589006 KX728_RS09030 WP_215804227.1 1863889..1866321(-) (clpC) [Streptococcus oralis strain 34]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAGAGTGCCTACATGGTTGCGAGCCATTTTGGAGCCCGTTACCTAGA
GTCTTGGCATTTATTGATTGCCATGTCCAATCACAGTTACAGTGTGGCAGGTGCAACTCTAAATGATTATCCTTATGAAA
TGGATCGTTTAGAAGAGGTTGCGTTGGAACTGACTGAAACGGATTATAGCCAAGACGAAACTTTTACGGAATTGCCCTTT
TCCCATCGTTTAGAAGTTCTCTTTGCAGAAGCAGAGTATGTAGCCTCAGTGGTCCACGCAAAGGTGCTAGGGACAGAACA
TGTCCTCTATGCGATCTTGCATGACGGCAATGCCTTGGCAACTCGCATCTTGGAGAGAGCAGGCTTTTCTTATGAAGACC
AGAAAGATCAGGTCAGAATTGCTGCTCTTCGTCGTAATCTAGAAGAGCGTGCAGGATGGACAAGAGAAGATCTCAAGGCT
TTGCGTCAACGTCATCGCACAGTAACTGACAAGCAAAATTCTATGGCCAATATGATGGGCATGCCTCAAGCTCAAAGTGG
CGGTTTAGAGGATTATACTCATGACCTGACGGAGCAAGCGCGTTCTGGCAAGTTAGAGCCAGTTATCGGTCGTGACAAGG
AAATCTCGCGTATGATTCAGATTTTGAGTCGGAAGACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTCGGGAAA
ACAGCTTTAGCACTTGGGCTTGCCCAGCGTATTGCCAGTGGGGACGTGCCAGCTGAAATGGTCAAGATGCGTGTTCTAGA
GCTTGATTTGATGAATGTCGTTGCAGGGACACGTTTCCGTGGTGACTTTGAAGAGCGTATGAACAACATCATCAAGGATA
TCGAGGAAGATGGCAAAGTGATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGTAGCGGTATTGACTCGACT
CTGGATGCAGCCAATATCTTGAAGCCAGCCTTAGCTCGCGGAACTCTGAGAACAGTTGGTGCAACCACTCAGGAAGAATA
CCAAAAACACATCGAAAAAGATGCTGCCCTTTCTCGTCGTTTTGCAAAAGTGACGATTGAAGAGCCAAGTCTAGCTGACA
GTATGACTATTTTGCAAGGTTTGAAGGCTACCTATGAGAAACACCACCGTGTGCAAATCACAGATGAAGCCGTTGAAACA
GCTGTCAAGATGGCGCATCGTTACTTGACTAGTCGTCACTTACCAGACTCTGCCATCGATCTATTGGATGAAGCGGCAGC
AACCGTTCAAAACAAATCCAAGCATGTGAAAGCAGACGATTCTGGTTTGAGTCCAGCTGACAAGGCACTTATGGATGGCA
AGTGGAAACAGGCAGCCCAGCTAATCGCAAAAGAAGAGGAAGTACCTGTCTACAAAGACTTGGTGACAGAGTCTGATATT
TTGACTACCTTGAGTCGCTTGTCAGGTATTCCAGTCCAAAAACTGACTCAAACGGATGCTAAGAAATACCTGAACTTGGA
AGCTGAACTACACAAACGTGTCATCGGTCAAGATCAAGCTGTTTCAAGTATTAGCCGTGCCATTCGCCGCAACCAGTCAG
GGATTCGCAGTCACAAGCGTCCGATTGGTTCCTTTATGTTCCTAGGGCCGACAGGAGTCGGTAAGACCGAATTGGCAAAG
GCTCTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAATACATGGAGAAATTCGCAGC
TAGCCGTCTCAATGGAGCACCTCCTGGCTATGTGGGCTACGAGGAAGGTGGGGAGTTGACCGAGAAAGTTCGCAACAAGC
CATACTCCGTTCTCCTCTTTGATGAGGTAGAGAAGGCCCACCCAGATATCTTTAATGTCCTCTTGCAGGTTCTGGACGAC
GGTGTCTTGACAGATAGTAAGGGACGCAAGGTGGACTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCGAC
GGCTCTTCGTGATGACAAGACGGTCGGATTTGGCGCCAAAGACCTTCGTTTTGACCAGGAAAATATGGAAAAACGAATCT
TTGAAGAGTTGAAAAAAGCTTATCGACCAGAGTTTATTAATCGTATTGATGAAAAGGTGGTCTTCCACAGCTTAGATAGC
AAACACATGCAAGAAATTGTCAAGATTATGGTGAAACCATTGATTGCTAGCCTCGCTGAGAAGGGCATCGATTTGAAACT
GCAAGCTTCAGCGTTGAAGTTACTAGCAAGCCAAGGATATGATCCAGAAATGGGAGCTCGCCCACTTCGCAGAACACTGC
AAACAGAAGTGGAAGACAAGTTGGCAGAACTCCTCCTTAAGGGAGAACTGGTAGCAGGCAAGACCCTCAAGATTGGTGTC
AAAGCAGGTCAGTTAAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (231-362)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (718-797)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (103-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-49)

• AAA lid domain (AAA_lid_9) (371-439)

• AAA domain (Cdc48 subfamily) (AAA_2) (540-711)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae D39	96.914	100	0.969
clpC	Streptococcus pneumoniae TIGR4	96.914	100	0.969
clpC	Streptococcus pneumoniae Rx1	96.914	100	0.969
clpC	Streptococcus mutans UA159	67.528	100	0.678
clpC	Streptococcus thermophilus LMD-9	66.585	100	0.669
clpC	Streptococcus thermophilus LMG 18311	66.462	100	0.668
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.212	100	0.501
clpC	Bacillus subtilis subsp. subtilis str. 168	44.951	100	0.451
clpE	Streptococcus mutans UA159	48.871	76.543	0.374
clpC	Lactococcus lactis subsp. cremoris KW2	46.73	77.407	0.362
clpE	Streptococcus pneumoniae Rx1	47.021	76.667	0.36
clpE	Streptococcus pneumoniae D39	47.021	76.667	0.36
clpE	Streptococcus pneumoniae R6	47.021	76.667	0.36
clpE	Streptococcus pneumoniae TIGR4	47.021	76.667	0.36