Detailed information NTG0588983

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: KX728_RS05780
• Genome accession: NZ_CP079724
• Coordinates: 1168782..1171022 (-)
• Length: 746 a.a.
• NCBI ID: WP_215804577.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain 34
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1163782..1176022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KX728_RS05755 (KX728_05750)	rplT	1165133..1165492 (-)	360	WP_000124830.1	50S ribosomal protein L20	-
KX728_RS05760 (KX728_05755)	rpmI	1165544..1165744 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
KX728_RS05765 (KX728_05760)	infC	1165777..1166307 (-)	531	WP_000848184.1	translation initiation factor IF-3	-
KX728_RS05770 (KX728_05765)	-	1166612..1167796 (-)	1185	WP_042902389.1	membrane protein	-
KX728_RS05775 (KX728_05770)	-	1167793..1168386 (-)	594	WP_042902390.1	ATP-binding cassette domain-containing protein	-
KX728_RS09360	-	1168419..1168624 (-)	206	Protein_1100	hypothetical protein	-
KX728_RS05780 (KX728_05775)	comEC/celB	1168782..1171022 (-)	2241	WP_215804577.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
KX728_RS05785 (KX728_05780)	comEA/celA/cilE	1171006..1171656 (-)	651	WP_042902392.1	helix-hairpin-helix domain-containing protein	Machinery gene
KX728_RS05790 (KX728_05785)	-	1171723..1172292 (-)	570	WP_049485310.1	GNAT family N-acetyltransferase	-
KX728_RS05795 (KX728_05790)	ald	1172469..1173581 (+)	1113	WP_084921952.1	alanine dehydrogenase	-
KX728_RS05800 (KX728_05795)	-	1173632..1174618 (-)	987	WP_084921953.1	PhoH family protein	-
KX728_RS05805 (KX728_05800)	-	1174699..1174914 (-)	216	WP_001232084.1	YozE family protein	-
KX728_RS05810 (KX728_05805)	-	1174938..1175516 (-)	579	WP_215804576.1	GrpB family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84723.06 Da
• Isoelectric Point: 9.3972

>NTDB_id=588983 KX728_RS05780 WP_215804577.1 1168782..1171022(-) (comEC/celB) [Streptococcus oralis strain 34]
MSQWIKNFPIPLIYLSFLLLWPYYAIFSVSYLALLGFVFLLICLFFQFPWKSAGRVLAICGVFGIWFLFQNWQQTQASQN
LADSVERVRILPDTIKVNGDSLSFRGKAEGRTFQVYYKLQSEEEKELFQALTDLHEIEIEGKLSEPEVQRNFGGFNYQAY
LKTQGIYQILTIKSIQSMKQVRSWDIGENLSGLRRKAVVWIKMRFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTILGLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPVTQFNFVFEWLENIIRLVSQLASRPLVFGQPNAWLLILLLVSLALVYDMRKNIKRLAGFSLFIVGLFFLTK
HPLENEIIMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIQAWQEKATTNNAQRTLIPYLKSRGVDKIDQLILTNTDK
EHIGDLLEVTKAFHVGEILVSKGSLTQKEFVAELEASQNKVRSVVAGENFPIFGSFLEVLSPRKIGDGNRDDSLVLYGKL
LDKHFLFTGNLKEKGEKDLLKQYPGLEVDVLKAGQHGAKTSSNPAFLEKIKPEITLISVGKSNRAKLPHQETLTRLESIK
SNIYRTDQQGAIRFTGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=588983 KX728_RS05780 WP_215804577.1 1168782..1171022(-) (comEC/celB) [Streptococcus oralis strain 34]
ATGTCACAGTGGATTAAGAATTTCCCTATCCCCCTAATCTATCTGAGTTTTCTGTTACTCTGGCCTTACTATGCCATTTT
CTCAGTATCTTATCTTGCTTTACTAGGCTTTGTTTTTCTACTCATCTGTCTCTTTTTTCAATTTCCTTGGAAATCGGCCG
GTAGAGTTCTAGCGATTTGTGGAGTTTTTGGAATTTGGTTTTTGTTTCAAAATTGGCAACAGACACAAGCAAGTCAAAAC
CTAGCGGATTCTGTTGAGAGGGTACGGATTTTACCAGATACCATCAAAGTCAATGGAGACAGTCTGTCCTTTCGGGGCAA
GGCTGAGGGCCGCACCTTCCAAGTTTATTATAAGCTACAGTCCGAGGAAGAGAAAGAGCTCTTTCAGGCCTTAACAGACC
TTCATGAGATAGAGATAGAAGGAAAACTTTCAGAGCCTGAAGTTCAGAGGAATTTTGGTGGCTTTAACTACCAAGCCTAT
CTGAAGACTCAAGGAATTTACCAAATTTTGACTATCAAGAGTATCCAGTCAATGAAACAGGTTAGAAGTTGGGATATAGG
AGAAAATCTGTCTGGTTTACGTCGGAAGGCTGTAGTTTGGATCAAGATGCGCTTTCCAGATCCTATGCGCAATTATATGA
CAGGTCTTCTTTTAGGACATTTGGACACGGACTTTGAGGAGATGAATGAGCTCTATTCCAGTCTTGGAATTATCCATCTC
TTTGCCTTGTCGGGTATGCAGGTAGGCTTTTTCATGGATGCCTTTAAGAAACTCCTCTTGCGATTGGGCTTAACTCAAGA
AAAGTTGAAGTGGCTAACTTATCCCTTTTCTCTTATCTATGCAGGTCTGACAGGATTTTCAGCATCTGTTATTCGCAGTC
TCTTGCAAAAGTTACTGGCCCAACATGGTGTTAAGGGTTTGGATAATTTTGCCTTGACGATCCTTGGCCTCTTTATCATC
ATGCCCAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCATACGCTTTTATCTTGACCATGACTAGTAAAGAAGG
GGAGGGACTCAAGGCTGTTGCTAGAGAAAGTCTGGTCATTTCCTTGGGAATATTGCCTATTCTATCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATCCTTTTGACCTTTGTATTTTCCTTTCTGTTTGATGTGGTCTTTTTGCCACTTTTGTCCATC
TTATTTATTCTGTCTTTTGTTTACCCAGTCACTCAGTTTAACTTTGTCTTTGAGTGGTTGGAGAACATCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGGCCTCTGGTCTTTGGTCAACCCAATGCATGGCTGTTGATTCTACTGTTAGTTTCATTAGCCT
TGGTCTATGACATGAGGAAAAACATCAAAAGACTAGCAGGATTTAGTCTCTTTATTGTGGGTCTCTTTTTCCTGACCAAG
CATCCACTTGAAAATGAAATCATCATGTTGGATGTGGGGCAAGGTGAAAGTATTTTCCTACGGGATGTAACTGGTAAAAC
CATTCTCATAGATGTGGGTGGTAAGGCAGAATCTGACAAGAAAATCCAAGCTTGGCAAGAAAAGGCGACAACCAACAATG
CCCAGAGAACCTTGATTCCCTATCTTAAAAGTCGAGGAGTAGACAAGATTGACCAGCTGATTTTGACAAATACAGATAAG
GAGCATATTGGCGATTTGCTGGAGGTAACCAAGGCTTTTCATGTCGGAGAGATTTTAGTATCAAAAGGAAGTCTGACACA
GAAGGAATTTGTAGCGGAACTAGAAGCAAGTCAAAACAAGGTACGTAGTGTGGTAGCTGGGGAGAATTTCCCGATTTTTG
GCAGTTTCTTAGAAGTCCTATCTCCAAGGAAGATTGGAGATGGGAATCGTGATGATTCTCTGGTTCTTTATGGAAAACTT
TTGGATAAGCACTTTCTCTTCACAGGAAATTTGAAAGAGAAGGGAGAGAAGGATCTTCTAAAGCAATACCCTGGCTTAGA
GGTGGATGTCCTGAAAGCAGGCCAACATGGTGCTAAAACCTCATCAAATCCAGCTTTCCTAGAAAAAATCAAACCAGAAA
TTACTCTCATTTCAGTCGGAAAGAGCAATCGTGCGAAACTCCCCCATCAGGAAACCTTGACACGACTGGAAAGTATCAAG
AGTAATATCTACCGAACTGACCAGCAAGGGGCTATCCGCTTTACAGGGTGGAATAGTTGGAGAATTGAAACGGTTCGTTA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (28-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	87.668	100	0.877
comEC/celB	Streptococcus mitis NCTC 12261	86.711	99.866	0.866
comEC/celB	Streptococcus pneumoniae TIGR4	86.193	100	0.862
comEC/celB	Streptococcus pneumoniae Rx1	85.657	100	0.857
comEC/celB	Streptococcus pneumoniae D39	85.657	100	0.857
comEC/celB	Streptococcus pneumoniae R6	85.657	100	0.857
comEC	Lactococcus lactis subsp. cremoris KW2	44.804	99.33	0.445