Detailed information NTG0588811

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KX797_RS12550
• Genome accession: NZ_CP079715
• Coordinates: 2508861..2509904 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain V8
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2503861..2514904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KX797_RS12520 (KX797_12520)	-	2504279..2505535 (-)	1257	WP_001795438.1	aminopeptidase	-
KX797_RS12525 (KX797_12525)	-	2505538..2505738 (-)	201	WP_000180461.1	DUF1128 family protein	-
KX797_RS12530 (KX797_12530)	-	2505885..2506349 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
KX797_RS12535 (KX797_12535)	-	2506356..2506631 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
KX797_RS12540 (KX797_12540)	-	2506909..2508126 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
KX797_RS12545 (KX797_12545)	vraR	2508242..2508871 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
KX797_RS12550 (KX797_12550)	vraS	2508861..2509904 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
KX797_RS12555 (KX797_12555)	liaF	2509901..2510602 (-)	702	WP_115287762.1	cell wall-active antibiotics response protein LiaF	-
KX797_RS12560 (KX797_12560)	-	2510617..2511003 (-)	387	WP_219098861.1	hypothetical protein	-
KX797_RS12565 (KX797_12565)	map	2511220..2511978 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
KX797_RS12570 (KX797_12570)	-	2512565..2513551 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
KX797_RS12575 (KX797_12575)	-	2514041..2514454 (-)	414	WP_001549145.1	hypothetical protein	-
KX797_RS12580 (KX797_12580)	-	2514483..2514593 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=588811 KX797_RS12550 WP_001017131.1 2508861..2509904(-) (vraS) [Staphylococcus aureus strain V8]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=588811 KX797_RS12550 WP_001017131.1 2508861..2509904(-) (vraS) [Staphylococcus aureus strain V8]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1