Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   N580_RS11475 Genome accession   NZ_CP079206
Coordinates   2236618..2238414 (+) Length   598 a.a.
NCBI ID   WP_005725465.1    Uniprot ID   A0A4V3BI87
Organism   Lactobacillus crispatus 2029     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2231618..2243414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N580_RS11450 (N580_11460) - 2232510..2232887 (-) 378 WP_005718180.1 hypothetical protein -
  N580_RS11455 (N580_11465) - 2233034..2233582 (+) 549 WP_005727414.1 GNAT family N-acetyltransferase -
  N580_RS13310 - 2233897..2234453 (+) 557 Protein_2217 PBECR4 domain-containing protein -
  N580_RS11465 (N580_11480) - 2234461..2235150 (-) 690 WP_005725467.1 DUF554 domain-containing protein -
  N580_RS11470 (N580_11485) - 2235217..2236452 (-) 1236 WP_005725466.1 LCP family protein -
  N580_RS11475 (N580_11490) pepF 2236618..2238414 (+) 1797 WP_005725465.1 oligoendopeptidase F Regulator
  N580_RS11480 (N580_11495) - 2238566..2238781 (+) 216 WP_005723825.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  N580_RS11485 (N580_11500) - 2238785..2239192 (+) 408 WP_005723824.1 type II toxin-antitoxin system death-on-curing family toxin -
  N580_RS11490 (N580_11505) - 2239306..2239581 (-) 276 WP_005723823.1 bacteriocin immunity protein -
  N580_RS11495 (N580_11510) - 2239585..2239803 (-) 219 WP_005726358.1 TIGR04139 family peptide modification target -
  N580_RS11500 (N580_11515) - 2239977..2240273 (-) 297 WP_005725464.1 bacteriocin immunity protein -
  N580_RS11505 (N580_11520) - 2240289..2240549 (-) 261 WP_005727422.1 thioredoxin domain-containing protein -
  N580_RS11510 (N580_11525) - 2240737..2241915 (+) 1179 WP_005727388.1 IS256 family transposase -
  N580_RS11515 (N580_11530) - 2242093..2242239 (-) 147 WP_005723821.1 hypothetical protein -
  N580_RS11520 (N580_11535) - 2242249..2242395 (-) 147 WP_005727423.1 hypothetical protein -
  N580_RS11525 (N580_11540) - 2242538..2243395 (-) 858 WP_005727342.1 IS982-like element ISLh1 family transposase -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68019.87 Da        Isoelectric Point: 4.6935

>NTDB_id=588257 N580_RS11475 WP_005725465.1 2236618..2238414(+) (pepF) [Lactobacillus crispatus 2029]
MAIPTRNEVPEELKWDLTRIFKNDDEWEQAYAAAQEKVAKLAELKGTLAKSGKNLYESLTKILAVKRDVENIYVYATMSS
DVDTSNSHYLGYVSRVQSLANQFEAATSFINPEILSIPSDKLEQFKQAEPRLKDYAHYLETITNKRPHTLPAEQEKLIAD
AGDALSVSENTFNVLTNSDMEYGYVQDDDGNMEQLSDGLYSLLIQSQNRDVRKGAFDTLYATYGQFQNSLASTLSGVVKK
HNYNARVHKYNSAREAALADNGVPVAVYDTLIQEVDSHLDLLHRYVALRKKILGLKDLQMWDMYVPLTGRPSLSYNFEEA
KETAKKALAPLGEDYLKHVDYIFNNRVIDPIESKNKVTGAYSGGAYDTDPYELLNWEDNIDSLYTLVHETGHSVHSWYTR
NTQPYVYGDYPIFVAEIASTTNENILTEYFLDHITDPKTRAFILNYYLDSFKGTLFRQTQFAVFEQFLHEADAKGEPLTA
DTLDDVYGQINQHYYGDSVEPGGDIALEWSRIPHFYYNFYVYQYATGFAAATALANKVVHGTPAERDAYLGFLKAGSSDY
PTEIMKRAGVDMTKPDYLEDAFKTFEKRLNEFESLIEK

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=588257 N580_RS11475 WP_005725465.1 2236618..2238414(+) (pepF) [Lactobacillus crispatus 2029]
ATGGCAATTCCAACTAGAAACGAAGTCCCTGAAGAGCTTAAATGGGACTTAACCCGTATTTTTAAAAATGACGATGAATG
GGAGCAAGCTTATGCAGCTGCACAAGAAAAAGTGGCTAAACTTGCTGAATTAAAAGGTACACTAGCTAAATCAGGCAAGA
ACCTGTACGAGAGCTTAACCAAAATCTTAGCTGTTAAACGTGATGTGGAAAATATCTACGTTTACGCTACCATGTCCAGC
GATGTTGATACTTCTAATTCGCACTATCTCGGCTACGTCAGCCGGGTACAAAGTTTGGCTAACCAGTTTGAGGCTGCAAC
AAGTTTTATTAATCCTGAAATCTTGAGTATCCCTAGTGATAAGCTTGAGCAATTTAAGCAAGCTGAACCTAGATTAAAGG
ATTACGCACACTATCTTGAAACAATTACTAACAAGCGTCCTCATACATTACCTGCTGAGCAAGAAAAATTGATCGCCGAT
GCTGGGGATGCTTTAAGTGTTTCTGAAAATACCTTTAACGTTTTGACCAACTCCGACATGGAATACGGTTACGTTCAAGA
CGATGACGGCAATATGGAACAATTATCAGATGGCCTTTATTCTTTGCTGATCCAATCCCAAAATCGTGATGTCAGAAAAG
GTGCTTTTGATACACTTTATGCCACTTATGGACAGTTCCAAAATTCCTTGGCTTCAACTTTGTCTGGCGTTGTAAAAAAG
CACAACTATAACGCACGTGTGCACAAGTATAATTCAGCTCGTGAAGCTGCTTTAGCCGATAATGGCGTACCCGTAGCAGT
TTATGACACTTTAATCCAGGAAGTTGATTCACACCTAGACTTACTTCACCGTTATGTTGCGCTACGTAAAAAGATCTTAG
GCCTGAAGGATCTGCAAATGTGGGACATGTATGTGCCACTAACCGGAAGACCTTCTCTTTCATACAATTTCGAAGAAGCA
AAAGAGACAGCAAAAAAGGCTTTGGCTCCACTTGGTGAAGACTACTTGAAGCATGTTGACTATATTTTTAATAATCGTGT
CATCGACCCAATAGAATCTAAAAACAAGGTAACTGGTGCCTACTCCGGTGGTGCTTATGATACCGATCCTTATGAGTTGC
TCAACTGGGAAGATAACATCGATTCACTTTATACTTTAGTCCACGAAACTGGTCACTCCGTTCACTCCTGGTACACTCGC
AATACTCAACCTTACGTTTACGGCGACTATCCAATCTTTGTGGCTGAAATTGCTTCAACTACTAATGAAAATATTTTGAC
CGAATATTTCTTAGACCACATTACCGATCCTAAGACGCGGGCCTTTATCTTAAATTACTACCTTGATTCATTTAAAGGCA
CTTTATTCCGTCAAACTCAATTTGCCGTGTTTGAACAATTCTTGCACGAAGCCGATGCTAAGGGAGAACCACTGACCGCT
GACACTTTAGACGACGTTTACGGTCAAATTAATCAGCATTATTACGGCGATAGCGTTGAACCAGGCGGCGATATTGCCCT
TGAATGGTCACGAATTCCACACTTCTACTACAATTTCTATGTGTACCAATATGCGACTGGCTTTGCGGCTGCAACGGCAT
TAGCAAACAAGGTGGTTCATGGAACGCCTGCTGAGAGGGATGCCTACCTTGGTTTCCTTAAAGCTGGTTCAAGTGATTAC
CCAACTGAGATCATGAAGCGTGCTGGCGTAGACATGACTAAGCCTGACTACTTAGAAGATGCCTTCAAGACTTTTGAAAA
ACGGTTGAACGAATTTGAAAGCTTGATTGAGAAATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(113-181)

Peptidase family M3 (Peptidase_M3)

(203-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V3BI87

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.602

99.164

0.512